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EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer

Cell Reports(2022)10.1016/j.celrep.2022.111827Source: DataRank Database

EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 33 times.

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Open Access33 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (23 grants)Impact (FWCI 3.94)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Jaemoo Chun ORCID,Jung Seok Hwang,Chaoyun Pan ORCID,Jie Li ORCID,Austin C. Boese ORCID

Live enrichment

PubMed:36516759 PMC:PMC9813823 OpenAlex:https://openalex.org/W4311310061

Winship Cancer Institute

Grant: NIH / NCI P30 CA138292

National Cancer Institute

Grant: P30 CA138292

National Institutes of Health

Grant: P01 CA257906

National Institutes of Health

Grant: R01 CA269782

National Institutes of Health

Grant: F99 CA264407

National Institutes of Health

Grant: P50 CA217691

National Institutes of Health

Grant: R01 CA207768

National Institutes of Health

Grant: R01 CA266613

National Institutes of Health

Grant: R37 CA249305

National Institutes of Health

Grant: R01 CA175316

National Institutes of Health

Grant: DoD W81XWH-21-1-0213

National Institutes of Health

Grant: 1R01CA269782-01

Platinum-induced lipid reprogramming and tumor immune microenvironment in SCLC

National Institutes of Health

Grant: 1P01CA257906-01A1

Deciphering LKB1-associated immunotherapy resistance in lung adenocarcinoma (LUAD)

National Institutes of Health

Grant: 5P30CA138292-11

Winship Cancer Institute Cancer Center Support Grant

National Institutes of Health

Grant: 1P50CA217691-01A1

Emory University Lung Cancer SPORE

National Institutes of Health

Grant: 5R01CA266613-04

Decoding and targeting saccharopine pathway in cancer metastasis

National Institutes of Health

Grant: 5R37CA249305-02

The role of NFIB-MAST1 signaling in mediating adaptive cisplatin resistance in SCLC

National Institutes of Health

Grant: 5R01CA207768-02

Role of MAST1 kinase in cisplatin resistant cancers

National Institutes of Health

Grant: 1F99CA264407-01

Metabolic reprogramming and tumor progression in LKB1 deficient NSCLC

National Institutes of Health

Grant: 5R01CA175316-07

Transcription-dependent and -independent signaling of RSK2 in cancer metastasis

US Department of Defense

Integrated Cellular Imaging Core, Emory University

American Cancer Society

FWCI

3.94

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttps://doi.org/10.1016/j.celrep.2022.111827

publisherhttps://doi.org/10.1016/j.celrep.2022.111827

publisherhttps://api.elsevier.com/content/article/PII:S2211124722017193?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722017193?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36516759

Fields of Study

Lung Cancer Treatments and MutationsCancer, Hypoxia, and MetabolismCancer Cells and Metastasis0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

HumansLung NeoplasmsPhosphorylationCyclic AMP Response Element-Binding ProteinRibosomal Protein S6 Kinases, 90-kDaCell Line, TumorErbB Receptors

Keywords

Cancer researchRibosomal s6 kinaseMetastasisCREBEpidermal growth factor receptorCyclin-dependent kinase 8PhosphorylationTranscription factorBiologySignal transductionCancerCell biologyNotch signaling pathwayP70-S6 Kinase 1Protein kinase BTyrosine phosphorylationEGFRTumorNon-small cell lung carcinomaRsk2Egfr MutationsCamp Response Element-binding ProteinRibosomal S6 Kinase 2Glutamate Dehydrogenase 1Gdh1Cp: CancerEpidermal Growth Factor Receptor 1Oncogenic Kinase SignalingErbB ReceptorsLung NeoplasmsCell Line, TumorHumansCyclic AMP Response Element-Binding ProteinRibosomal Protein S6 Kinases, 90-kDaArticle

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer

FAIR Checklist

Authors (15)

Funding (23 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)