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Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging

Cell Reports(2023)10.1016/j.celrep.2022.111970Source: DataRank Database

Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging is a research paper published in Cell Reports (2023). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Open Access22 citations

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Enrichment:Funding (7 grants)Impact (FWCI 1.53)OA: goldTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Michelle Curley ORCID,Flávia A. Graça ORCID,Maricela Robles‐Murguia ORCID,Abbas Shirinifard ORCID,David Finkelstein ORCID

Live enrichment

PubMed:36640359 PMC:PMC9933915 OpenAlex:https://openalex.org/W4315484235

National Institute on Aging

Grant: R01AG055532

National Institute on Aging

Grant: R21AG079267

Alzheimer's Association

Grant: AARG-NTF-22-973220

National Institutes of Health

Grant: 5R01AG055532-04

Regulation of Mitochondrial Gene Expression and Function by GDF11 Signaling

National Institutes of Health

Grant: 1R21AG079267-01

Mapping tauopathy-induced changes in subcellular proteostasis with compartment-targeted sensors

National Institutes of Health

American Lebanese Syrian Associated Charities

FWCI

1.53

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124722018745/pdf

publisherhttp://www.cell.com/article/S2211124722018745/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124722018745?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722018745?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2022.111970

Fields of Study

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AgingAnimalsDrosophilaHumansEndopeptidasesTranscription FactorsUbiquitinsHomeodomain ProteinsDrosophila ProteinsProteasome Endopeptidase ComplexProteolysis

Keywords

ProteostasisBiologyProteasesCell biologyTFEBProteaseTranscription factorAutophagyProteasomeLysosomeUbiquitinGene knockdownRNA interferenceDeubiquitinating enzymeDownregulation and upregulationBiochemistryGeneEnzymeAgingSkeletal musclehuntingtinPeptidaseProtein Quality ControlPitxPtx1Cp: Molecular BiologyCp: Cell BiologyBetatryHomeodomain ProteinsProteasome Endopeptidase ComplexQH301-705.5ArticleEndopeptidasesProteolysisHumansAnimalsDrosophila ProteinsDrosophilaBiology (General)UbiquitinsTranscription Factors

Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging

FAIR Checklist

Authors (9)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)