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PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

Cell Reports(2023)10.1016/j.celrep.2023.112091Source: DataRank Database

PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle is a research paper published in Cell Reports (2023). On theSindex it has a DataRank of 0. It has been cited 17 times.

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Open Access17 citations

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Enrichment:Funding (26 grants)Impact (FWCI 1.58)OA: goldTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Wenjing Wu ORCID,Volha V. Malechka,Yusuke Takahashi ORCID,Jian‐xing Ma ORCID,Gennadiy Moiseyev ORCID

Live enrichment

PubMed:36763501 PMC:PMC10406976 OpenAlex:https://openalex.org/W4319455315

National Eye Institute

Grant: EY021725

National Institutes of Health

Grant: EY012231

National Institutes of Health

Grant: EY019309

National Institutes of Health

Grant: EY028949

National Institutes of Health

Grant: EY030472

National Institutes of Health

Grant: EY032930

National Institutes of Health

Grant: EY032931

National Institutes of Health

Grant: EY033330

National Institutes of Health

Grant: GM122744

NEI NIH HHS

Grant: R01 EY012231

NEI NIH HHS

Grant: R01 EY028949

NEI NIH HHS

Grant: R01 EY032931

NEI NIH HHS

Grant: R01 EY033330

NEI NIH HHS

Grant: R01 EY032930

NEI NIH HHS

Grant: P30 EY021725

NEI NIH HHS

Grant: R01 EY030472

NIGMS NIH HHS

Grant: P30 GM122744

NEI NIH HHS

Grant: R01 EY019309

National Institutes of Health

Grant: 2P30EY021725-06

P30-Center Core Grant for Vision Research

National Institutes of Health

Grant: 5R01EY032931-06

Dysregulation of Wnt signaling in subretinal fibrosis in AMD

National Institutes of Health

Grant: 5R01EY019309-10

A new pathogenic mechanism for diabetic retinopathy

National Institutes of Health

Grant: 5R01EY030472-04

Small Molecule PPAR-alpha Agonism as a Novel Approach to Treat Eye Vascular Diseases

National Institutes of Health

Grant: 7R01EY032930-02

Studies of retinyl ester hydrolase in the visual cycle

National Institutes of Health

Grant: 7R01EY028949-04

A Novel Pathogenic Pathway for Diabetic Keratopathy

National Institutes of Health

Grant: 1R01EY033330-01

cGAS-STING signaling in diabetic retinopathy

National Institutes of Health

Grant: 5R01EY012231-10

Studies of RPE65

FWCI

1.58

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2023.112091

publisherhttps://doi.org/10.1016/j.celrep.2023.112091

publisherhttps://api.elsevier.com/content/article/PII:S221112472300102X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472300102X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36763501

Fields of Study

Retinal Development and DisordersAdvanced Fluorescence Microscopy TechniquesRetinoids in leukemia and cellular processes0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsMiceElectroretinographyRetinal Pigment EpitheliumRetinaldehydeRetinyl EstersVitamin AAcyltransferasesLipase

MeSH Terms

Retinyl EstersAcyltransferasesAnimalsElectroretinographyLipaseRetinaldehydeVitamin AMiceRetinal Pigment Epithelium

Keywords

RetinalChemistryCell biologyVisual phototransductionNeuroscienceRetinaBiologyBiochemistrylipid dropletsPnpla2RetinosomesRetinyl Ester Hydrolase11-Cis-retinolCp: MetabolismRetinyl EstersQH301-705.5Retinal Pigment EpitheliumLipaseArticleMiceElectroretinographyRetinaldehydeAnimalsBiology (General)Vitamin AAcyltransferases

PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

FAIR Checklist

Authors (6)

Funding (26 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)