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Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes

Cell Reports(2023)10.1016/j.celrep.2023.112448Source: DataRank Database

Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes is a research paper published in Cell Reports (2023). On theSindex it has a DataRank of 0. It has been cited 37 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access37 citations

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Linked data & code

cellosaurus rrid pdb

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (17 grants)Impact (FWCI 6.37)OA: goldTopics (66)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Erin Smith ORCID,Chantell S. Evans ORCID,C. Alexander Boecker ORCID,Erika L.F. Holzbaur ORCID,Dan Dou ORCID

Live enrichment

PubMed:37133994 PMC:PMC10304398 OpenAlex:https://openalex.org/W4367625974

Aligning Science Across Parkinson’s

Grant: ASAP-000350

Mechanisms of mitochondrial damage control by PINK1 and Parkin

Deutsche Forschungsgemeinschaft

Grant: BO 5434/2-1

National Institutes of Health

Grant: 1 F31 NS124249–01

National Institutes of Health

Grant: R35 GM126950

National Institutes of Health

Grant: T32-AG-000255

Michael J. Fox Foundation for Parkinson's Research

Grant: MJFF-019411

Michael J. Fox Foundation for Parkinson's Research

Grant: MJFF-021130

Michael J. Fox Foundation for Parkinson's Research

Grant: MJFF-15100

NINDS NIH HHS

Grant: R01 NS060698

NIA NIH HHS

Grant: T32 AG000255

NINDS NIH HHS

Grant: F31 NS124249

National Institutes of Health

Grant: 5T32AG000255-20

Training in age related neurodegenerative diseases

National Institutes of Health

Grant: 2R35GM126950-06

Molecular Mechanisms of Axonal Transport and Organelle Dynamics

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5F31NS124249-02

Investigating the Role of LRRK2 Hyperactivity in Autophagic and Synaptic Deficits

Howard Hughes Medical Institute

Jackson Laboratory

FWCI

6.37

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.cell.com/article/S221112472300459X/pdf

publisherhttp://www.cell.com/article/S221112472300459X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S221112472300459X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472300459X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2023.112448

Fields of Study

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and TreatmentsLysosomal Storage Disorders Research0301 basic medicine0303 health sciences03 medical and health sciencesHumansADP-Ribosylation Factor 6AutophagosomesAxonal TransportDyneinsGTP PhosphohydrolasesKinesinsLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MutationParkinson DiseasePhosphoprotein PhosphatasesPhosphorylation

MeSH Terms

Leucine-Rich Repeat Serine-Threonine Protein Kinase-2AutophagosomesADP-Ribosylation Factor 6Axonal TransportDyneinsHumansMutationParkinson DiseasePhosphoprotein PhosphatasesPhosphorylationKinesinsGTP Phosphohydrolases

Keywords

LRRK2GTPaseSmall GTPaseCell biologyKinasePhosphataseAxoplasmic transportProtein phosphatase 2BiologyPhosphorylationChemistrySignal transductionBiochemistryGeneMutationKinesinAutophagyParkinson’s DiseaseAxonal TransportCytoplasmic DyneinArf6Rab GtpasesPpm1hCp: Cell BiologyQH301-705.5AutophagosomesDyneinsKinesinsParkinson DiseaseLeucine-Rich Repeat Serine-Threonine Protein Kinase-2ArticleGTP PhosphohydrolasesADP-Ribosylation Factor 6Phosphoprotein PhosphatasesHumansBiology (General)

Sustainable Development Goals

SDG 0: Good health and well-being