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TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet

Cell Reports(2024)10.1016/j.celrep.2024.113673Source: DataRank Database

TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 10 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access10 citations

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 1.64)OA: goldTopics (75)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Arya Y. Nakhe ORCID,Prasanna K. Dadi ORCID,Matthew T. Dickerson ORCID,Jordyn R. Dobson,Karolina E. Zaborska ORCID

Live enrichment

PubMed:38206814 PMC:PMC10961926 OpenAlex:https://openalex.org/W4390708560

Vanderbilt University

Grant: DK020593

NIH

Grant: F31 DK118855

NIH

Grant: R01DK115620

NIH

Grant: R01DK129340

NIH

Grant: R01DK097392

NIGMS NIH HHS

Grant: T32 GM139800

NIDDK NIH HHS

Grant: T32 DK007563

NIDDK NIH HHS

Grant: P30 DK020593

NCI NIH HHS

Grant: P30 CA068485

NIDDK NIH HHS

Grant: R01 DK136768

NIDDK NIH HHS

Grant: F31 DK109625

National Institutes of Health

Grant: 2P30CA068485-14

Program Leaders

National Institutes of Health

Grant: 2T32DK007563-11

MULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGY

National Institutes of Health

Grant: 5R01DK129340-04

Molecular Mechanisms Regulating Pancreatic Delta Cell Function and Dysfunction

National Institutes of Health

Grant: 5R01DK115620-03

Designing selective TALK-1 inhibitors to reduce beta-cell dysfunction in diabetes

National Institutes of Health

Grant: 5R01DK097392-08

Two-Pore-Domain Potassium Channels as Novel Targets for Modulating Islet Hormone Secretion

National Institutes of Health

Grant: 1F31DK118855-01

The role of endoplasmic reticulum (ER) localized TALK-1 channels in beta-cell insulin secretion, mitochondrial function and the ER stress response

National Institutes of Health

Grant: 5T32GM139800-05

Initiative for Maximizing Student Development (IMSD) at Vanderbilt

National Institutes of Health

Grant: 1F31DK109625-01

TALK-1 channels as a novel target to modulate basal insulin secretion and obesity

Università degli Studi di Padova

FWCI

1.64

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124724000019/pdf

publisherhttp://www.cell.com/article/S2211124724000019/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124724000019?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724000019?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2024.113673

Fields of Study

Mitochondrial Function and PathologyAdipose Tissue and MetabolismPancreatic function and diabetes0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsMiceAdenosine TriphosphateCalciumDiabetes MellitusDietEndoplasmic ReticulumGlucoseHomeostasisInsulinInsulin SecretionInsulin-Secreting CellsMice, KnockoutMitochondriaPotassium Channels, Tandem Pore Domain

MeSH Terms

Insulin SecretionAdenosine TriphosphateAnimalsCalciumDiabetes MellitusDietEndoplasmic ReticulumGlucoseHomeostasisInsulinMitochondriaMice, KnockoutPotassium Channels, Tandem Pore DomainInsulin-Secreting CellsMice

Keywords

HomeostasisGlucose homeostasisSecretionInternal medicineInsulinEndocrinologyFunction (biology)BiologyMitochondrionCell biologyCellInsulin resistanceMedicineBiochemistryMitochondriaMetabolismEndoplasmic reticulumDiabetesinsulin secretionCalcium HandlingPancreatic Β-cellK2pTwo-pore-domain Potassium ChannelCp: Cell BiologyCp: MetabolismTalk-1Mice, KnockoutQH301-705.5ArticleDietMiceAdenosine TriphosphateGlucosePotassium Channels, Tandem Pore DomainInsulin-Secreting CellsDiabetes MellitusAnimalsCalciumBiology (General)

Sustainable Development Goals

SDG 0: Good health and well-being