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A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis

Cell Reports(2024)10.1016/j.celrep.2024.114004Source: DataRank Database

A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 21 times.

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0DataRank · unranked

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Open Access21 citations

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Enrichment:Funding (4 grants)Impact (FWCI 3.45)OA: goldTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Chengliang Wang ORCID,Atri Ta ORCID,Morena S. Havira ORCID,Jianbin Ruan ORCID,Vijay Rathinam ORCID

Live enrichment

PubMed:38522070 PMC:PMC11095105 OpenAlex:https://openalex.org/W4393097829

National Institutes of Health

Grant: R56 AI132850

National Institutes of Health

Grant: R01AI119015

National Institutes of Health

Grant: R01AI158435

NIAID NIH HHS

Grant: R01 AI132850

FWCI

3.45

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.cell.com/article/S2211124724003322/pdf

publisherhttp://www.cell.com/article/S2211124724003322/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124724003322?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724003322?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2024.114004

Fields of Study

Inflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxide

MeSH Terms

PyroptosisGasderminsAnimalsBacterial ToxinsEscherichia coli InfectionsHumansLipopolysaccharidesMacrophagesMice, Inbred C57BLCaspasesPhosphate-Binding ProteinsIntracellular Signaling Peptides and ProteinsApoptosis Regulatory ProteinsMiceCaspase 3Caspases, InitiatorInterleukin-1betaEnterohemorrhagic Escherichia coliInflammasomes

Keywords

PyroptosisCaspase 1Innate immune systemInflammasomeMicrobiologyBiologyCaspaseLipopolysaccharideToxinShiga toxinExotoxinEscherichia coliPathogenImmune systemCell biologyApoptosisImmunologyInflammationProgrammed cell deathBiochemistryGeneCaspase-3EHECEnterohemorrhagic E. ColiCaspase-11Noncanonical InflammasomeGasdermin DCp: MicrobiologyCp: Immunology

A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis

FAIR Checklist

Authors (7)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)