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Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation

Cell Reports(2024)10.1016/j.celrep.2024.114193Source: DataRank Database

Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 41 times.

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Enrichment:Funding (20 grants)OA: goldTopics (55)IDs (PubMed, PMC)Annotations (1)

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Authors (13)

Ju-Yeon Jo ORCID,Chih‐Yen Wang ORCID,Heavin Oh,Jiangshan Zhan ORCID,Tiffany J. Choy ORCID

Live enrichment

PubMed:38709635 PMC:PMC11210630

NHLBI NIH HHS

Grant: R01 HL130249

NIH

Grant: UM1HG006348

NIDDK NIH HHS

Grant: R01 DK114356

NINDS NIH HHS

Grant: R01 NS110859

NINDS NIH HHS

Grant: R01 NS126287

NIH

Grant: R01GM073857

NIH

Grant: P50HD103555

National Institute of Neurological Disorders and Stroke

Grant: 2R01NS110859

National Multiple Sclerosis Society

Grant: RG-1907-34551

National Institutes of Health

Grant: 1R01DK114356-01

An anti-diabetic microRNA that promotes metabolically healthy obesity

National Institutes of Health

Grant: 5R01NS110859-04

Deciphering the Daam2-VHL signaling axis in oligodendrocyte development and white matter injury

National Institutes of Health

Grant: 5R01GM073857-07

Mechanism and Uses of Transmembrane Helix Insertion by Soluble Peptides

National Institutes of Health

Grant: 5R01NS126287-03

Deciphering Mechanisms of Astrocyte-BBB Interaction in Normal and Ischemic Stroke

National Institutes of Health

Grant: 5UM1HG006348-10

Consortium for large-scale production and phenotyping of knockout mice (UM1)

National Institutes of Health

Grant: 1P50HD103555-01

Baylor College of Medicine Intellectual and Developmental Disabilities Research Center

National Institutes of Health

Grant: 3R01HL130249-06S1

Noradrenergic mechanisms in breathing and respiratory pathophysiologies

Baylor College of Medicine

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Diana Helis Henry Medical Research Foundation Inc

Lions Medical Research Foundation

goldLicense: CC BY

Europe_PMChttps://europepmc.org/articles/PMC11210630

Europe_PMChttps://europepmc.org/articles/PMC11210630?pdf=render

https://doi.org/10.1016/j.celrep.2024.114193

https://pubmed.ncbi.nlm.nih.gov/38709635

http://dx.doi.org/10.1016/j.celrep.2024.114193

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

Blood-Brain BarrierBrainAstrocytesAnimalsMice, Inbred C57BLHumansMiceSodium-Bicarbonate SymportersSignal TransductionMaleChemokine CCL2StrokeReceptors, CCR2

Keywords

Nitric oxideArginineAstrocyteEndotheliaCaveolinIschemic strokeBlood-Brain BarrierPh RegulationSlc4a4Ccl2-ccr2Cp: NeuroscienceMaleMedical SciencesBioinformaticsQH301-705.5Receptors, CCR2610DiseasesInbred C57BLArticleBiomedical InformaticsMiceHemic and Lymphatic DiseasesReceptorsMedical SpecialtiesMedicine and Health SciencesAnimalsHumansBiology (General)Chemokine CCL2Sodium-Bicarbonate SymportersBrainHematologyMice, Inbred C57BLStrokeOncologyAstrocytesCCR2Signal Transduction

Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation

FAIR Checklist

Authors (13)

Funding (20 grants)

Open Access

Topics

Annotations (Europe PMC)