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ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models

Cell Reports(2024)10.1016/j.celrep.2024.114829Source: DataRank Database

ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Enrichment:Funding (13 grants)OA: goldTopics (40)IDs (PubMed, PMC)Annotations (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (18)

Zachary R. Russell ORCID,Alex Shimura Yamashita ORCID,Madeline E. West,Abigail G Parrish,Julia Rose Walker

Live enrichment

PubMed:39365700 PMC:PMC11572037

National Cancer Institute

Grant: 75N91019D00024

National Cancer Institute

Grant: R35 CA253119-01A1

National Cancer Institute

Grant: S10OD26919

National Institutes of Health

Grant: SCR_022616

NCI NIH HHS

Grant: U54 CA243125

NCI NIH HHS

Grant: P30 CA015704

NIH HHS

Grant: S10 OD026919

NCI NIH HHS

Grant: R35 CA253119

National Institutes of Health

Grant: 3P30CA015704-42S2

Cancer Center Support Grant

National Institutes of Health

Grant: 1S10OD026919-01A1

Fred Hutch Preclinical 3T MRI

National Institutes of Health

Grant: 3R35CA253119-03S1

The role and mechanism of alternative RNA splice variants and gene fusions as drivers of cancer

National Institutes of Health

Grant: 1U54CA243125-01

Biology and therapy of C11orf95-RELA fusion-driven ependymoma

U.S. Department of Health and Human Services

goldLicense: CC BY NC ND

publisherhttps://doi.org/10.1016/j.celrep.2024.114829

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11572037/pdf/nihms-2031310.pdf

repositoryhttps://doaj.org/article/4470af9805e444e2b122261c594c9aa1

Europe_PMChttps://europepmc.org/articles/PMC11572037

Europe_PMChttps://europepmc.org/articles/PMC11572037?pdf=render

Fields of Study

03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsHumansMiceGliomaDisease Models, AnimalReceptor, trkAReceptor, trkBReceptor, trkCOncogene Proteins, FusionProtein Kinase InhibitorsMAP Kinase Signaling SystemDrug Resistance, Neoplasm

Keywords

Gene fusionTargeted TherapyMouse ModelsRtkTrametinibPediatric GliomaEntrectinibNtrkLarotrectinibRepotrectinibCp: CancerOncogene Proteins, FusionQH301-705.5MAP Kinase Signaling SystemGliomaArticleMiceDisease Models, AnimalDrug Resistance, NeoplasmAnimalsHumansReceptor, trkBReceptor, trkCBiology (General)Receptor, trkAProtein Kinase Inhibitors

ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models

FAIR Checklist

Authors (18)

Funding (13 grants)

Open Access

Topics

Annotations (Europe PMC)