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ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer

Cell Reports(2024)10.1016/j.celrep.2024.114991Source: DataRank Database

ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0.362. It has been cited 9 times, with 9 citing works in its 1-hop citation network.

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0.362DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access9 citations · 9 citing works in its network

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Linked data & code

geo cellosaurus hpa doi

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE259252

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 1.64)OA: goldTopics (66)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 96%Citation Network 4%

Base Score Contribution

0.345

From this paper's citation signal

Citation Network Contribution

0.0162

From 3 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 9 citers.

CRISPR screening approaches in breast cancer research
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The Targeted Inhibition of Histone Lysine Demethylases as a Novel Promising Anti-Cancer Therapeutic Strategy—An Update on Recent Evidence
Cancers20253 citations255 referencesContributes 0.005
Discovery and structural studies of histone demethylases
Frontiers in Epigenetics and Epigenomics20252 citations252 referencesContributes 0.004
Realgar‐Induced CNS Toxicity: Exploring OTC‐Mediated Ornithine Regulation of ZBTB7A Inhibits Astrocyte Glycolysis Based on the Liver–Brain Axis
Advanced Science20250 citations56 referencesContributes 0.000
Context-aware gene dependency modeling via graph attention networks for precision oncology
Journal of Translational Medicine20250 citations61 referencesContributes 0.000

Authors (24)

Marco Seehawer ORCID,Zheqi Li ORCID,Andriana Patmanidis,Triet M. Bui ORCID,Pierre Foidart ORCID

Live enrichment

PubMed:39570746 PMC:PMC11694571 OpenAlex:https://openalex.org/W4404538295

National Cancer Institute

Grant: R35 CA197623

National Cancer Institute

Grant: P01 CA250959

NCI NIH HHS

Grant: T32 CA236754

National Institutes of Health

Grant: 1P01CA250959-01

New therapeutic vulnerabilities in breast cancer

National Institutes of Health

Grant: 5R35CA197623-03

Targeting intratumor heterogeneity in breast cancer

National Institutes of Health

Ludwig Center at Harvard

National Center for Advancing Translational Sciences

FWCI

1.64

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2024.114991

publisherhttps://doi.org/10.1016/j.celrep.2024.114991

publisherhttps://api.elsevier.com/content/article/PII:S2211124724013421?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724013421?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39570746

Fields of Study

Epigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchCancer-related gene regulation0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

AnimalsBreast NeoplasmsDNA-Binding ProteinsFemaleHistonesHumansPromoter Regions, GeneticTranscription FactorsGene Expression Regulation, NeoplasticNF-kappa BCell Line, TumorGene Regulatory NetworksRetinoblastoma-Binding Protein 2

Keywords

Breast cancerBasal (medicine)BiologyCell biologyCancerCancer researchGeneticsEndocrinologyhistone demethylaseMitochondrial SignalingCrispr ScreenCp: CancerKDM5A protein, humanBreast Neoplasms/pathologyQH301-705.5Histones/metabolismTranscription Factors/geneticsOncologieBreast NeoplasmsBreast Neoplasms/geneticsSciences de la santé humaineArticleHistonesRetinoblastoma-Binding Protein 2/metabolismCell Line, TumorHumansAnimalsTranscription Factors/metabolismGene Regulatory NetworksHuman health sciencesBiology (General)Promoter Regions, GeneticZBTB7A protein, humanRetinoblastoma-Binding Protein 2/geneticsDNA-Binding Proteins/metabolismBiochemistry, Genetics and Molecular Biology (all)NF-kappa BPromoter Regions, Genetic/geneticsDNA-Binding ProteinsGene Expression Regulation, NeoplasticOncologyBreast Neoplasms/metabolismNF-kappa B/metabolismFemaleRetinoblastoma-Binding Protein 2DNA-Binding Proteins/geneticsTranscription Factors

Sustainable Development Goals

SDG 0: Good health and well-being