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Microglia degrade Alzheimer’s amyloid-beta deposits extracellularly via digestive exophagy

Cell Reports(2024)10.1016/j.celrep.2024.115052Source: DataRank Database

Microglia degrade Alzheimer’s amyloid-beta deposits extracellularly via digestive exophagy is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 31 times.

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Open Access31 citations

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Enrichment:Funding (16 grants)OA: goldTopics (41)IDs (PubMed, PMC)Annotations (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Fernando Gonzàlez Ibáñez ORCID,Katherine Picard ORCID,Lucy Funes ORCID,Mohammadparsa Khakpour,Gunnar K. Gouras ORCID

Live enrichment

PubMed:39644493 PMC:PMC11760508

Cure Alzheimer's Fund

Grant: CAF-211540-02

Swedish Research Council

Grant: 637-2013-503/D0050301

National Research Council Canada

Grant: CRC-2019-00407

National Institutes of Health

Grant: R01-HL093324

National Institutes of Health

Grant: RF1-AG078244

NHLBI NIH HHS

Grant: R01 HL093324

NIA NIH HHS

Grant: RF1 AG078244

National Institutes of Health

Grant: 3R01HL093324-11S1

Macrophage-lipoprotein Interactions

National Institutes of Health

Grant: 1RF1AG078244-01A1

Role of microglial lysosomes in amyloid-A-beta degradation

Swedish Research Council

Grant: unidentified

unidentified

Canada Foundation for Innovation

Leon Levy Foundation

Consejo Nacional de Humanidades, Ciencias y Tecnologías

Canada Research Chairs

Vanderbilt University Medical Center

Mexico State Government Mexican Council for Science and Technology

goldLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.celrep.2024.115052

publisherhttps://api.elsevier.com/content/article/PII:S2211124724014037?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724014037?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11760508/pdf/nihms-2044462.pdf

repositoryhttps://doaj.org/article/4cc3189622f347658520a736aac382bc

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

MicrogliaSynapsesLysosomesAnimalsHumansMiceAlzheimer DiseaseSignal TransductionExocytosisProto-Oncogene Proteins c-aktAmyloid beta-PeptidesPhosphatidylinositol 3-KinasesPlaque, Amyloid

Keywords

Electron microscopyLysosomeAcid phosphataseMicrogliaAlzheimer’s diseaseAmyloid-beta5XfadLysosomal PhExtracellular DegradationCp: NeuroscienceDigestive ExophagyAmyloid beta-PeptidesQH301-705.5Plaque, AmyloidArticleExocytosisMicePhosphatidylinositol 3-KinasesAlzheimer DiseaseSynapsesAnimalsHumansBiology (General)LysosomesProto-Oncogene Proteins c-aktSignal Transduction

Microglia degrade Alzheimer’s amyloid-beta deposits extracellularly via digestive exophagy

FAIR Checklist

Authors (9)

Funding (16 grants)

Open Access

Topics

Annotations (Europe PMC)