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Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer

Cell Reports(2024)10.1016/j.celrep.2024.115089Source: DataRank Database

Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0.455. It has been cited 12 times, with 10 citing works in its 1-hop citation network.

N/A

0.455DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access12 citations · 10 citing works in its network

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Linked data & code

geo gen cellosaurus hpa uniprot

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE252840 GSE252842 GSE252843 GSE252897 GSE277606

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (17 grants)OA: goldTopics (41)IDs (PubMed, PMC)Annotations (5)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 85%Citation Network 15%

Base Score Contribution

0.385

From this paper's citation signal

Citation Network Contribution

0.0698

From 6 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 10 citers.

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer
Cell Reports20259 citations67 referencesContributes 0.034
Circular RNA–based therapy targeting metabolic vulnerability of fatty acid synthesis overcomes castration-resistant prostate cancer
Proceedings of the National Academy of Sciences20252 citations60 referencesContributes 0.018
Evolving roles for the androgen receptor and its protein interactome in castration-resistant prostate cancer
Oncogene20259 citations149 referencesContributes 0.015
Genomic Crosstalk Between Nuclear Receptors in Hormone-dependent Cancers
Endocrinology20251 citations139 referencesContributes 0.005
Alterations in AR-FOXA1 signaling in prostate cancer progression and therapeutic resistance
Journal of the National Cancer Center20252 citations241 referencesContributes 0.005

Authors (20)

Mannan Nouri ORCID,Jiaqian Liang,Shaoyong Chen ORCID,Andreas Varkaris ORCID,Betul Ersoy-Fazlioglu ORCID

Live enrichment

PubMed:39709604 PMC:PMC11921039

NCI NIH HHS

Grant: P50 CA272390

NCI NIH HHS

Grant: R01 CA259058

National Cancer Institute

Grant: R01CA272934

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu

Grant: W81XWH-21-1-0234

NCI NIH HHS

Grant: U54 CA156732

Canadian Institutes of Health Research

Grant: PJT-173331

NCI NIH HHS

Grant: R01 CA251555

NCI NIH HHS

Grant: R01 CA262577

Association of Schools and Colleges of Optometry

Grant: 2021A010981

NCI NIH HHS

Grant: R01 CA227237

Prostate Cancer Foundation

Grant: 18YOUN24

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu

Grant: 114Z491

National Cancer Institute

Grant: P01 CA163227

NCI NIH HHS

Grant: P50 CA090381

U.S. Department of Defense

Grant: W81XVVH-20-100925

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

goldLicense: CC BY NC ND

publisherhttps://doi.org/10.1016/j.celrep.2024.115089

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11921039/pdf/nihms-2052726.pdf

repositoryhttps://doaj.org/article/2f2b85dedf46431d9d37f79b462cfcfe

Europe_PMChttps://europepmc.org/articles/PMC11921039

Europe_PMChttps://europepmc.org/articles/PMC11921039?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

Cell Line, TumorChromatinHumansProstatic NeoplasmsBenzamidesNitrilesPhenylthiohydantoinProtein IsoformsReceptors, AndrogenGene Expression Regulation, NeoplasticAlternative SplicingMaleNFI Transcription FactorsProstatic Neoplasms, Castration-Resistant

Keywords

TranscriptionAndrogen receptorEpigeneticschromatinprostate cancerFoxa1Nuclear Factor ICp: Molecular BiologyCp: CancerMaleQH301-705.5Prostatic NeoplasmsArticleGene Expression Regulation, NeoplasticNFI Transcription FactorsAlternative SplicingProstatic Neoplasms, Castration-ResistantReceptors, AndrogenCell Line, TumorBenzamidesPhenylthiohydantoinNitrilesHumansProtein IsoformsBiology (General)