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Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs

Cell Reports(2025)10.1016/j.celrep.2024.115092Source: DataRank Database

Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 16 times.

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Open Access16 citations

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geo cellosaurus refseq

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (27 grants)OA: goldTopics (34)IDs (PubMed, PMC)Annotations (3)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Aidan C. Manning ORCID,Jenna M. Lentini ORCID,Jonathan C. Howard ORCID,Felix Dalwigk,Reza Maroofian ORCID

Live enrichment

PubMed:39786990 PMC:PMC11831618

National Science Foundation

Grant: 1552126

CAREER: Elucidating the Targets and Functions of Mammalian tRNA methyltransferase orthologs

Medical Research Council

Grant: MR/S005021/1

MRC Strategic Award to establish an International Centre for Genomic Medicine in Neuromuscular Diseases

Medical Research Council

Grant: G0601943

MRC Centre for Neuromuscular Diseases in Children and Adults

Medical Research Council

Grant: MR/S01165X/1

Leveraging the power of genomics and transcriptomics to revolutionise the diagnosis and understanding of neurological disorders

Deutsche Forschungsgemeinschaft

Grant: 259130777-SFB 1177

Deutsche Forschungsgemeinschaft

Grant: 325871075-SFB 1309

Deutsche Forschungsgemeinschaft

Grant: 325871075-SFB 1309and 259130777-SFB 1177

Wellcome Trust

Grant: WT104033AIA

Wellcome Trust

Grant: WT093205MA

National Institutes of Health

Grant: R01 GM141038

National Institutes of Health

Grant: R01 GM143145

Wellcome Trust

Grant: 104033

Wellcome Trust

Grant: 093205

Development of an Institute of Neurology Next Generation Sequencing Facility Equipment Grant.

Deutsche Forschungsgemeinschaft

Grant: 259130777/SFB 1177

Molecular and Functional Characterization of Selective Autophagy

National Institutes of Health

Grant: 1R01GM141038-01

Molecular functions of the TRMT1 tRNA modification enzyme

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01GM143145-03

Mechanism and functions of DALRD3-dependent tRNA modification

Great Ormond Street Hospital Charity

Memphis Research Consortium

Wellcome Trust

Rosetrees Trust

UCLH Biomedical Research Centre

Multiple System Atrophy Trust

Ataxia UK

Muscular Dystrophy Association

Muskelsvindfonden

University of Rochester

goldLicense: cc-by-nc

publisherhttps://doi.org/10.1016/j.celrep.2024.115092

publisherhttps://api.elsevier.com/content/article/PII:S2211124724014438?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724014438?httpAccept=text/plain

repositoryhttps://escholarship.org/content/qt1zp3d9bx/qt1zp3d9bx.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11831618/pdf/nihms-2052732.pdf

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

HumanstRNA MethyltransferasesRNA, TransferGuanosineRNA StabilityMethylationHEK293 Cells

Keywords

TranslationtRNAIntellectual DisabilityParalogRna ModificationTrmt1Trm1Cp: Molecular BiologyTrmt1lM2,2g570QH301-705.5RNA StabilityMethylationArticleRNA, TransferHumans2GBiology (General)tRNA MethyltransferasesGuanosinem2TransferHEK293 CellsRNA

Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs

FAIR Checklist

Authors (17)

Funding (27 grants)

Open Access

Topics

Annotations (Europe PMC)