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The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation

Cell Reports(2024)10.1016/j.celrep.2024.115101Source: DataRank Database

The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 0.65)OA: goldTopics (29)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Sungki Hong ORCID,Shota Yoshida ORCID,Vinamra Swaroop,Brady Curtin,Ken Inoki ORCID

Live enrichment

PubMed:39708321 OpenAlex:https://openalex.org/W4405650636

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK124709

National Institute of General Medical Sciences

Grant: GM145631

FWCI

0.65

Citation Percentile

0.7%

Citation Trend

2025

goldLicense: cc-by-nc

journalhttps://doi.org/10.1016/j.celrep.2024.115101

publisherhttps://doi.org/10.1016/j.celrep.2024.115101

publisherhttps://api.elsevier.com/content/article/PII:S2211124724014529?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724014529?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39708321

Fields of Study

Ubiquitin and proteasome pathwaysHistone Deacetylase Inhibitors ResearchPI3K/AKT/mTOR signaling in cancer

MeSH Terms

Ras Homolog Enriched in Brain ProteinMechanistic Target of Rapamycin Complex 1Amino AcidsAnimalsCarrier ProteinsHumansLysosomesMonomeric GTP-Binding ProteinsUbiquitin-Protein LigasesCullin ProteinsAdaptor Proteins, Signal TransducingMiceUbiquitinationHEK293 Cells

Keywords

Ubiquitin ligaseChemistrymTORC1DNA ligaseRHEBUbiquitinCell biologyBiochemistryEnzymeBiologySignal transductionPI3K/AKT/mTOR pathway