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Lipid droplet efferocytosis attenuates proinflammatory signaling in macrophages via TREM2- and MS4A7-dependent mechanisms

Cell Reports(2025)10.1016/j.celrep.2025.115310Source: DataRank Database

Lipid droplet efferocytosis attenuates proinflammatory signaling in macrophages via TREM2- and MS4A7-dependent mechanisms is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 20 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access20 citations

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Enrichment:Funding (6 grants)Impact (FWCI 8.14)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

You Lu ORCID,Xiaoxue Qiu ORCID,Zhimin Chen ORCID,Yuwei Tang ORCID,Ziyi Meng ORCID

Live enrichment

PubMed:39954254 PMC:PMC11973828 OpenAlex:https://openalex.org/W4407478852

NIDDK NIH HHS

Grant: P30 DK020572

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: DK136179

NIDDK NIH HHS

Grant: R01 DK136179

American Heart Association Inc

Grant: 846890

National Institutes of Health

University of Michigan

FWCI

8.14

Citation Percentile

1.0%

Citation Trend

2022

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://www.cell.com/cell-reports/pdf/S2211-1247(25)00081-6.pdf

publisherhttps://www.cell.com/cell-reports/pdf/S2211-1247(25)00081-6.pdf

journalhttps://doi.org/10.1016/j.celrep.2025.115310

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39954254

repositoryhttps://hdl.handle.net/1805/48076

Fields of Study

Phagocytosis and Immune RegulationImmune cells in cancerImmune Cell Function and Interaction

MeSH Terms

NLR Family, Pyrin Domain-Containing 3 ProteinEfferocytosisAnimalsHumansInflammationLiverLysosomesMacrophagesMaleMembrane GlycoproteinsMice, Inbred C57BLPhagocytosisReceptors, ImmunologicSignal TransductionMiceInflammasomesLipid Droplets

Keywords

Proinflammatory cytokineEfferocytosisCell biologyLipid signalingTREM2MacrophageChemistrySignal transductionPhagocytosisInflammationBiologyImmunologyBiochemistryMicrogliaIn vitroMacrophageslipid dropletsInflammatory ResponseNlrp3 InflammasomeCp: ImmunologyCp: MetabolismMs4a7

Sustainable Development Goals

SDG 0: Zero hunger

Lipid droplet efferocytosis attenuates proinflammatory signaling in macrophages via TREM2- and MS4A7-dependent mechanisms

FAIR Checklist

Authors (10)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)