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Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development

Cell Reports(2025)10.1016/j.celrep.2025.115495Source: DataRank Database

Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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Enrichment:Funding (4 grants)Impact (FWCI 3.80)OA: goldTopics (47)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Weiping Shen,William Wen ORCID,Yuyoung Joo ORCID,Yutong Xue ORCID,Aaron Park

Live enrichment

PubMed:40184251 PMC:PMC12070812 OpenAlex:https://openalex.org/W4409190920

National Institute on Aging

Grant: Z01 AG000657-08

Intramural NIH HHS

Grant: ZIA AG000689

Intramural NIH HHS

Grant: Z01 AG000657

National Institutes of Health

FWCI

3.80

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.celrep.2025.115495

publisherhttps://doi.org/10.1016/j.celrep.2025.115495

publisherhttps://api.elsevier.com/content/article/PII:S2211124725002669?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725002669?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40184251

Fields of Study

Chromosomal and Genetic VariationsCancer therapeutics and mechanismsAdvanced biosensing and bioanalysis techniquesMedicineBiologyAnimalsRNA, Small InterferingGerm CellsDrosophila ProteinsDNA Transposable ElementsDrosophila melanogasterGene SilencingDNA Topoisomerases, Type IMalePiwi-Interacting RNA

MeSH Terms

Piwi-Interacting RNAAnimalsDNA Transposable ElementsDNA Topoisomerases, Type IDrosophila melanogasterGerm CellsMaleGene SilencingDrosophila ProteinsRNA, Small Interfering

Keywords

Piwi-interacting RNABiogenesisTransposable elementGene silencingCell biologyGerm cellBiologyGeneticsGenomeGeneGerm cellsFertilityOogenesisTransposonTopoisomerasePirnaPiwiAubTop3bTdrd3Cp: Molecular BiologyCp: Developmental Biology

Sustainable Development Goals

SDG 0: Zero hunger

Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development

FAIR Checklist

Authors (17)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)