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BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways

Cell Reports(2025)10.1016/j.celrep.2025.115779Source: DataRank Database

BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

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Open Access2 citations

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Enrichment:Funding (11 grants)Impact (FWCI 1.55)OA: goldTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (24)

Subhiksha Nandakumar ORCID,Nabila Zaman,Prathiksha Prabhakaraalva,Sarah Ann King,Teja Kalidindi ORCID

Live enrichment

PubMed:40448998 PMC:PMC12316453 OpenAlex:https://openalex.org/W4410879030

Icahn School of Medicine at Mount Sinai

Grant: P30CA196521

U.S. Department of Defense

Grant: W81XWH-19-1- 0470

U.S. Department of Defense

Grant: W81XWH-18-1-0330

National Cancer Institute

Grant: R01CA274967

National Cancer Institute

Grant: 5P01CA228696-02

National Cancer Institute

Grant: P30 CA008748

NCI NIH HHS

Grant: P01 CA163227

NCI NIH HHS

Grant: P01 CA228696

National Institutes of Health National Cancer Institute

Grant: R01 CA262536

National Institutes of Health

Prostate Cancer Foundation

FWCI

1.55

Citation Percentile

0.8%

Citation Trend

2025

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2025.115779

publisherhttps://doi.org/10.1016/j.celrep.2025.115779

publisherhttps://api.elsevier.com/content/article/PII:S2211124725005509?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725005509?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40448998

Fields of Study

Prostate Cancer Treatment and ResearchUbiquitin and proteasome pathwaysCancer, Lipids, and MetabolismMaleProstatic Neoplasms, Castration-ResistantHumansProto-Oncogene Proteins c-bcl-2Signal TransductionReceptors, AndrogenAnimalsCell Line, TumorMiceAndrogen AntagonistsCarcinogenesisGene Expression Regulation, NeoplasticPhosphatidylinositol 3-Kinases

MeSH Terms

Androgen AntagonistsAnimalsHumansMaleReceptors, AndrogenSignal TransductionGene Expression Regulation, NeoplasticProto-Oncogene Proteins c-bcl-2Phosphatidylinositol 3-KinasesCell Line, TumorMiceCarcinogenesisProstatic Neoplasms, Castration-Resistant

Keywords

CrosstalkProstate cancerCastrationProstateCancer researchBiologyMedicineBioinformaticsCancerInternal medicineEngineeringHormoneHedgehogSignalingbcl 2Combination therapyARCellular PlasticityAdtPi3 Kinase SignalingVenetoclaxCp: Cancer

Sustainable Development Goals

SDG 0: Zero hunger