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Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease

Cell Reports(2025)10.1016/j.celrep.2025.115798Source: DataRank Database

Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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Enrichment:Funding (10 grants)OA: goldTopics (17)IDs (PubMed, PMC)Annotations (3)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Yuqian Chang ORCID,Eunice Lee ORCID,Valia P Leifer,Eddy Hsi Chun Wang ORCID,Rolando Pérez‐Lorenzo ORCID

Live enrichment

PubMed:40531623 PMC:PMC12854772

National Institutes of Health

Grant: S10OD030282

Native American Agriculture Fund

Grant: CU23-4215

Native American Agriculture Fund

Grant: 73035959

Native American Agriculture Fund

Grant: K01AR070291

American Association of Immunologists

Grant: F31AR077409

American Association of Immunologists

Grant: UV286BO9J0

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Grant: R01 AR084005

NIAMS NIH HHS

Grant: P50 AR070588

National Alopecia Areata Foundation

Pfizer

goldLicense: cc-by-sa

publisherhttps://www.cell.com/action/showPdf?pii=S2211124725005698

publisherhttps://api.elsevier.com/content/article/PII:S2211124725005698?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725005698?httpAccept=text/plain

repositoryhttps://doaj.org/article/c796c203ba224ff8897cb9bff5bd42f1

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12854772/

MeSH Terms

CD8-Positive T-LymphocytesClone CellsAnimalsMice, Inbred C3HMiceAlopecia AreataDisease Models, AnimalReceptors, Antigen, T-CellSingle-Cell Analysis

Keywords

Hair follicleAlopecia areataautoimmune diseaseClonal T Cell ExpansionCp: ImmunologyTcr Retrogenic MicePathogenic Cd8(+) T CellsTargeted T Cell Depletion