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Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals

Cell Reports(2025)10.1016/j.celrep.2025.116065Source: DataRank Database

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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geo cellosaurus gen gwas refsnp doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)Impact (FWCI 7.65)OA: goldTopics (41)IDs (PubMed, PMC, OpenAlex)Annotations (6)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (23)

Xiaoshan Zhang ORCID,Zeping Zhao,Henry J. Taylor ORCID,Xuming Tang ORCID,Yuling Han ORCID

Live enrichment

PubMed:40737125 PMC:PMC12477748 OpenAlex:https://openalex.org/W4412822743

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: 5U01DK127777

National Institutes of Health

Grant: UC4-DK-112217

National Institutes of Health

Grant: 1-ZIA-HG000024

National Human Genome Research Institute

Grant: UC4-DK-112232

National Human Genome Research Institute

Grant: SCR_014393

National Human Genome Research Institute

Grant: U01-DK-123716

National Human Genome Research Institute

Grant: U01-DK-123594

NIDDK NIH HHS

Grant: U01 DK123716

NIDDK NIH HHS

Grant: U01 DK143498

NIDDK NIH HHS

Grant: R01 DK136005

NIDDK NIH HHS

Grant: U01 DK127777

NIDDK NIH HHS

Grant: U24 DK138515

NCI NIH HHS

Grant: P30 CA008748

NIDDK NIH HHS

Grant: U01 DK112217

NIDDK NIH HHS

Grant: UC4 DK112217

NIDDK NIH HHS

Grant: R01 DK142414

NIDDK NIH HHS

Grant: U24 DK097771

Intramural NIH HHS

Grant: ZIA HG000024

NIDDK NIH HHS

Grant: U01 DK123594

NIDDK NIH HHS

Grant: UC4 DK112232

FWCI

7.65

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2025.116065

publisherhttps://doi.org/10.1016/j.celrep.2025.116065

publisherhttps://api.elsevier.com/content/article/PII:S2211124725008368?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725008368?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40737125

Fields of Study

Pancreatic function and diabetesSingle-cell and spatial transcriptomicsDiabetes and associated disorders

MeSH Terms

Human Embryonic Stem CellsMultiomicsCalcium-Binding ProteinsDiabetes Mellitus, Type 1HumansIslets of LangerhansMembrane ProteinsApoptosisPolymorphism, Single NucleotideInsulin-Secreting CellsGenome-Wide Association StudySingle-Cell Analysis

Keywords

BiologyEmbryonic stem cellChromatinGeneticsInduced pluripotent stem cellComputational biologyGenome-wide association studyGeneSingle-nucleotide polymorphismCell typeEpigeneticsTranscriptomeCellGene expressionApoptosisDifferentiationCytokinetype 1 diabetesβ cellsGwasHpscsHuman Pancreatic IsletsMulti-omics ProfilingCp: MetabolismCp: GenomicsT1d-associated Signals

Sustainable Development Goals

SDG 0: Good health and well-being

Integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D-associated genes and regulatory signals

FAIR Checklist

Authors (23)

Funding (20 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)