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A capsular polysaccharide from a healthy human microbiota member activates a Lag-3-NK cell axis to restrain colon cancer and augment immunotherapy

Cell Reports(2025)10.1016/j.celrep.2025.116172Source: DataRank Database

A capsular polysaccharide from a healthy human microbiota member activates a Lag-3-NK cell axis to restrain colon cancer and augment immunotherapy is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 8 times.

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0DataRank · unranked

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Open Access8 citations

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geo gen cellosaurus uniprot nct doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)OA: goldTopics (25)IDs (PubMed, PMC)Annotations (6)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (30)

Kaylyn M. Bauer ORCID,William W. Tang ORCID,Emmanuel Stephen‐Victor ORCID,Rickesha Bell ORCID,D. Garrett Brown ORCID

Live enrichment

PubMed:40849910 PMC:PMC13270923

National Institutes of Health

Grant: TUBITAK-2232B-121C115

National Institutes of Health

Grant: TUBITAK-1001-122S337

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: 5P30CA042014-24

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: F32CA243501

NCI NIH HHS

Grant: K22 CA289144

Burroughs Wellcome Fund

National Cancer Institute

University of Utah

W. M. Keck Foundation

goldLicense: cc-by-sa

publisherhttps://doi.org/10.1016/j.celrep.2025.116172

publisherhttps://api.elsevier.com/content/article/PII:S221112472500943X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472500943X?httpAccept=text/plain

repositoryhttps://doaj.org/article/d90dbfaed5d249d0bab6ff0fc8596dac

repositoryhttps://hdl.handle.net/11147/18452

MeSH Terms

Killer Cells, NaturalAnimalsMice, Inbred C57BLHumansMiceColonic NeoplasmsPolysaccharides, BacterialAntigens, CDImmunotherapyFemaleMaleMicrobiotaGastrointestinal MicrobiomeLymphocyte Activation Gene 3 Protein

Keywords

CancerMicrobiologyNK cellsCapsulesColon cancertumor immunologyMicrobiomeLag-3Human SamplesCp: MicrobiologyCp: Cancer

A capsular polysaccharide from a healthy human microbiota member activates a Lag-3-NK cell axis to restrain colon cancer and augment immunotherapy

FAIR Checklist

Authors (30)

Funding (9 grants)

Open Access

Topics

Annotations (Europe PMC)