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Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer

Cell Reports(2025)10.1016/j.celrep.2025.116384Source: DataRank Database

Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (9 grants)Impact (FWCI 3.80)OA: goldTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (4)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Xueying Ma ORCID,Yunyun Zhou ORCID,Xiaodan Liu ORCID,Ting Zhang ORCID,William Kim ORCID

Live enrichment

PubMed:41046514 PMC:PMC12908447 OpenAlex:https://openalex.org/W4414826573

National Institutes of Health

Grant: T32GM142606

NCI NIH HHS

Grant: U54 CA221704

NCI NIH HHS

Grant: R37 CA283552

NCI NIH HHS

Grant: P30 CA006927

NIAID NIH HHS

Grant: R01 AI171568

National Cancer Institute

G. Harold and Leila Y. Mathers Foundation

Lung Cancer Research Foundation

W. W. Smith Charitable Trust

FWCI

3.80

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.cell.com/cell-reports/pdf/S2211-1247(25)01155-6.pdf

publisherhttps://www.cell.com/cell-reports/pdf/S2211-1247(25)01155-6.pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124725011556?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725011556?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2025.116384

Fields of Study

RNA modifications and cancerMicroRNA in disease regulationLung Cancer Research StudiesSpliceosomesAnimalsHumansLung NeoplasmsSmall Cell Lung CarcinomaMiceRNA-Binding ProteinsRNA Splicing FactorsCell Line, TumorCell DeathRNA, Double-StrandedTumor MicroenvironmentPhosphoproteinsFibroblastsRNA, Z-Form

MeSH Terms

RNA Splicing FactorsRNA, Z-FormAnimalsFibroblastsHumansLung NeoplasmsPhosphoproteinsRNA, Double-StrandedRNA-Binding ProteinsCell DeathSpliceosomesCell Line, TumorMiceSmall Cell Lung CarcinomaTumor Microenvironment

Keywords

SpliceosomeProgrammed cell deathImmunotherapyCancer immunotherapyImmune systemCellImmunogenic cell deathTumor microenvironmentsmall cell lung cancerNecroptosisSCLCZbp1Sf3b1Z-rnaSttsCp: Molecular BiologyCp: CancerSpliceosome-targeted Therapy

Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer

FAIR Checklist

Authors (8)

Funding (9 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)