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Autonomous STING signaling in Purkinje cells drives neurodegeneration independent of type I interferon

Cell Reports(2025)10.1016/j.celrep.2025.116480Source: DataRank Database

Autonomous STING signaling in Purkinje cells drives neurodegeneration independent of type I interferon is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (13 grants)Impact (FWCI 0.80)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Miranda Dunn,Gustavo Torres-Ramirez,Nicole Dobbs ORCID,Vikram G. Shakkottai ORCID,Nan Yan ORCID

Live enrichment

PubMed:41166304 PMC:PMC12746686 OpenAlex:https://openalex.org/W4415764759

National Institute of Neurological Disorders and Stroke

Grant: NS128285

National Institute of Neurological Disorders and Stroke

Grant: NS122825

National Institute of Neurological Disorders and Stroke

Grant: NS117424

National Institute of Neurological Disorders and Stroke

Grant: NS085054

National Cancer Institute

Grant: P30 CA142543

National Cancer Institute

Grant: SCR_017949

NINDS NIH HHS

Grant: R01 NS085054

NINDS NIH HHS

Grant: R01 NS117424

NINDS NIH HHS

Grant: R01 NS122825

NINDS NIH HHS

Grant: R01 NS128285

Grace Science Foundation

University of Pennsylvania

National Institutes of Health

FWCI

0.80

Citation Percentile

0.7%

Citation Trend

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.celrep.2025.116480

publisherhttps://doi.org/10.1016/j.celrep.2025.116480

publisherhttps://api.elsevier.com/content/article/PII:S2211124725012513?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725012513?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41166304

Fields of Study

interferon and immune responsesNeuroinflammation and Neurodegeneration MechanismsBacterial Infections and VaccinesMedicineBiologyAnimalsPurkinje CellsMembrane ProteinsSignal TransductionInterferon Type IMiceReceptor, Interferon alpha-betaMice, KnockoutMice, Inbred C57BLMicrogliaCerebellumSTING Protein

MeSH Terms

STING ProteinAnimalsCerebellumInterferon Type IMembrane ProteinsMice, Inbred C57BLPurkinje CellsSignal TransductionMicrogliaMice, KnockoutMiceReceptor, Interferon alpha-beta

Keywords

StingPurkinje cellNeurodegenerationStimulator of interferon genesSignal transductionInterferonConditional gene knockoutKnockout mousePurkinje cellsIFNneuroinflammationCp: NeuroscienceCp: Cell Biology

Autonomous STING signaling in Purkinje cells drives neurodegeneration independent of type I interferon

FAIR Checklist

Authors (6)

Funding (13 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)