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Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons

Cell Reports(2025)10.1016/j.celrep.2025.116746Source: DataRank Database

Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons is a research paper published in Cell Reports (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (10 grants)Impact (FWCI 0.00)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Parul Varma ORCID,Sara Mirsadeghi ORCID,J.M. Martín Caballero,Sergio Gamero-Alameda,Ali Seif Amir Hosseini ORCID

Live enrichment

PubMed:41422506 PMC:PMC12934246 OpenAlex:https://openalex.org/W4417526683

NIH

Grant: R21NS135514

NIH

Grant: R01NS0124855

NIH

Grant: R01NS113516

NIH

Grant: R21AG066496

NIH

Grant: U01DA054170

NINDS NIH HHS

Grant: R01 NS124855

Semmes Foundation

LGS Foundation

Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation

American Epilepsy Society

FWCI

0.00

Citation Percentile

0.4%

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.celrep.2025.116746

publisherhttps://doi.org/10.1016/j.celrep.2025.116746

publisherhttps://api.elsevier.com/content/article/PII:S2211124725015189?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124725015189?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41422506

Fields of Study

Neurogenesis and neuroplasticity mechanismsHereditary Neurological DisordersEpilepsy research and treatmentHumansHomeodomain ProteinsOrganoidsMutationTranscription FactorsNeuronsPeptidesCerebral CortexReceptors, CXCR4Spasms, InfantileMaleCell MovementCell ProliferationInterneurons

MeSH Terms

Cell MovementCerebral CortexHumansInterneuronsMaleMutationNeuronsOrganoidsPeptidesSpasms, InfantileTranscription FactorsHomeodomain ProteinsReceptors, CXCR4Cell Proliferation

Keywords

Ganglionic eminenceHomeoboxOrganoidInhibitory postsynaptic potentialInterneuronHuman brainProgenitor cellExcitatory postsynaptic potentialEpilepsyDownregulation and upregulationBrain DevelopmentOrganoidsArxInterneuron MigrationCp: Developmental BiologyCp: NeurosciencePoly-alanine Expansion

Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons

FAIR Checklist

Authors (13)

Funding (10 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)