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Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors

Cell Systems(2024)10.1016/j.cels.2024.03.002Source: DataRank Database

Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors is a research paper published in Cell Systems (2024). On theSindex it has a DataRank of 0. It has been cited 22 times.

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Open Access22 citations

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Enrichment:Funding (7 grants)Impact (FWCI 8.15)OA: greenTopics (24)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Matthew A. Spence ORCID,Mahakaran Sandhu,Dana C. Matthews,Jackie Chen ORCID,Colin J. Jackson ORCID

Live enrichment

PubMed:38537640 PMC:PMC11299162 OpenAlex:https://openalex.org/W4393190824

National Institutes of Health

Grant: DP2GM132682

Biological and Environmental Research

Grant: DE-SC0018409

U.S. Department of Energy

National Computational Infrastructure

Great Lakes Bioenergy Research Center

Office of Science

U.S. Department of Defense

FWCI

8.15

Citation Percentile

1.0%

Citation Trend

2020

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11299162/pdf/nihms-1977567.pdf

publisherhttps://api.elsevier.com/content/article/PII:S2405471224000620?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2405471224000620?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11299162

Fields of Study

Evolution and Genetic DynamicsGene Regulatory Network AnalysisCRISPR and Genetic Engineering

MeSH Terms

Phylogeny

Keywords

Fitness landscapeBiologyLac repressorRepressorEvolutionary biologyGeneticsFunction (biology)Computational biologyCrosstalkPhylogeneticsGeneTranscription factorEpistasisDMSProtein EvolutionAsrAncestral Sequence ReconstructionDeep Mutational ScanningTranscription RegulatorsSequence-function Relationships

Sustainable Development Goals

SDG 0: Zero hunger

Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors

FAIR Checklist

Authors (7)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)