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Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome

Cell Systems(2024)10.1016/j.cels.2024.12.002Source: DataRank Database

Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome is a research paper published in Cell Systems (2024). On theSindex it has a DataRank of 0. It has been cited 24 times.

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cellosaurus gen doi

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Enrichment:Funding (7 grants)OA: hybridTopics (28)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC)Annotations (3)

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Authors (3)

Kaden M. Southard ORCID,Thomas M. Norman ORCID,Eli Metzner ORCID

Live enrichment

PubMed:39689711 PMC:PMC11738662

NIGMS NIH HHS

Grant: DP2 GM140925

NCI NIH HHS

Grant: P30 CA008748

NHGRI NIH HHS

Grant: U01 HG012103

National Institutes of Health

Grant: 1DP2GM140925-01

Predictive engineering of cellular transcriptional state

National Institutes of Health

Grant: 2P30CA008748-43

MOUSE GENETICS

National Institute of General Medical Sciences

National Cancer Institute

hybridLicense: cc-by-nc-nd

publisherhttps://doi.org/10.1016/j.cels.2024.12.002

publisherhttps://api.elsevier.com/content/article/PII:S2405471224003661?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2405471224003661?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11738662/pdf/nihms-2040923.pdf

Europe_PMChttps://europepmc.org/articles/PMC11738662

Fields of Study

0206 medical engineering02 engineering and technology

MeSH Terms

Cell LineChromatinHumansGene Expression ProfilingChromatin Assembly and DisassemblySingle-Cell AnalysisTranscriptomeCRISPR-Cas SystemsEpigenome

Keywords

Functional genomicsGene Regulatory NetworksChromatin AccessibilitySingle-cell GenomicsCrispriPerturb-seqMultiomeEpigenomeGene Expression ProfilingHumansSingle-Cell AnalysisCRISPR-Cas SystemsTranscriptomeChromatin Assembly and DisassemblyArticleChromatinCell Line

GEX and ATAC count matrices for pEM040 sgRNA singlets

10.5281/zenodo.15116138Zenodo

GEX and ATAC count matrices for pEM040 sgRNA singlets

10.5281/zenodo.15116137Zenodo

Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome

FAIR Checklist

Authors (3)

Funding (7 grants)

Open Access

Topics

Linked Datasets (2)

Annotations (Europe PMC)