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scCausalVI disentangles single-cell perturbation responses with causality-aware generative model

Cell Systems(2025)10.1016/j.cels.2025.101443Source: DataRank Database

scCausalVI disentangles single-cell perturbation responses with causality-aware generative model is a research paper published in Cell Systems (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.54)OA: closedTopics (27)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Jae-Won Cho,Kai Cao ORCID,Jiankang Xiong,Martin Hemberg ORCID,Lin Wan ORCID

Live enrichment

PubMed:41197632 OpenAlex:https://openalex.org/W4415942985

National Key Research and Development Program of China Stem Cell and Translational Research

Grant: 2022YFA1004801

NIH HHS

Grant: OT2 OD033758

National Key Research and Development Program of China

Chan Zuckerberg Initiative

National Human Genome Research Institute

FWCI

1.54

Citation Percentile

0.8%

Citation Trend

2026

closedLicense: http://www.elsevier.com/open-access/userlicense/1.0/

publisherhttps://api.elsevier.com/content/article/PII:S2405471225002765?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2405471225002765?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cels.2025.101443

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41197632

Fields of Study

Single-cell and spatial transcriptomicsBioinformatics and Genomic NetworksGene Regulatory Network Analysis

MeSH Terms

COVID-19SARS-CoV-2Computer SimulationHumansSequence Analysis, RNAComputational BiologyGene Expression ProfilingSingle-Cell AnalysisTranscriptome

Keywords

Causal modelGenerative grammarIn silicoVariation (astronomy)Generative modelBenchmarkingGene regulatory networkIn Silico PerturbationMulti-source Data IntegrationCausal DisentanglementCell-state-specific Treatment EffectDeep Structural Causal ModelOut-of-distribution PredictionPerturbational AnalysisResponsive Cell Identification

scCausalVI disentangles single-cell perturbation responses with causality-aware generative model

FAIR Checklist

Authors (6)

Funding (5 grants)

Impact

Open Access

Topics