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Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.006Source: DataRank Database

Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets is a research paper published in Cell chemical biology (2024). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

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Open Access4 citations

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Linked data & code

Changes in lipid composition of phosphonate treated Plasmodium falciparum · Dryad

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 1.17)OA: greenTopics (36)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (16)

Sunil Kumar Narwal ORCID,Stephanie Kabeche ORCID,Daniel Abegg ORCID,Vandana Thathy ORCID,Fiona Hackett

Live enrichment

PubMed:39137783 OpenAlex:https://openalex.org/W4401512694

Bill and Melinda Gates Foundation

Grant: INV-033538

U.S. Department of Defense

Grant: T32 GM113854

U.S. Department of Defense

Grant: W81XWII2210520

U.S. Department of Defense

Grant: W81XWH2210520

Wellcome Trust

Grant: 220318/A/20/Z

National Institutes of Health

Grant: R01 AI109023

National Institutes of Health

Grant: R33 AI127581

National Institutes of Health

Grant: R33 AH27581

UKRI Medical Research Council

Grant: CC2129

NIAID NIH HHS

Grant: R01 AI141366

NIGMS NIH HHS

Grant: R01 GM145886

FWCI

1.17

Citation Percentile

0.8%

Citation Trend

2024

2025

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11457795/pdf/nihms-2017805.pdf

publisherhttps://api.elsevier.com/content/article/PII:S2451945624003088?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2451945624003088?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11457795/

Fields of Study

HIV/AIDS drug development and treatmentSynthesis and Catalytic ReactionsPneumocystis jirovecii pneumonia detection and treatmentAntimalarialsPlasmodium falciparumOrganophosphonatesHumansParasitic Sensitivity TestsMolecular StructureStructure-Activity Relationship

MeSH Terms

AntimalarialsHumansPlasmodium falciparumStructure-Activity RelationshipMolecular StructureParasitic Sensitivity TestsOrganophosphonates

Keywords

Plasmodium falciparumNatural productSerine hydrolaseSerineArylBiologyAntiparasitic agentChemistryBiochemistryMalariaEnzymePharmacologyAlkylactivity-based probesalky/aryl phosphonatescovalent probesdrug resistancelipid metabolismserine hydrolases

Changes in lipid composition of phosphonate treated Plasmodium falciparum

10.5061/dryad.b5mkkwhmjDryad