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An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates

Cell Host & Microbe(2021)10.1016/j.chom.2021.08.002Source: DataRank Database

An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates is a research paper published in Cell Host & Microbe (2021). On theSindex it has a DataRank of 0. It has been cited 81 times.

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Open Access81 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (23 grants)Impact (FWCI 10.28)OA: hybridTopics (80)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (54)

Wenlong Dai ORCID,Urja Bhatt ORCID,Cécile Hérate ORCID,Pauline Maisonnasse ORCID,Jessica A. Chichester ORCID

Live enrichment

PubMed:34428428 PMC:PMC8346325 OpenAlex:https://openalex.org/W3187307462

National Institute of Allergy and Infectious Diseases

Grant: NR-596

National Institute of Allergy and Infectious Diseases

Grant: VERO C1008

Centers for Disease Control and Prevention Office of Public Health Preparedness and Response

Grant: CK000490

NIH

Grant: R01 AI146779

National Institute of General Medical Sciences

Grant: T32 GM007753

National Institute of General Medical Sciences

Grant: T32 AI007245

NEI NIH HHS

Grant: P30 EY003790

NCEZID CDC HHS

Grant: U01 CK000490

National Institutes of Health

Grant: 3U24AI126683-09S1

Nonhuman Primate Reagent Resource

National Institutes of Health

Grant: 5T32AI007245-25

Molecular Basis of Viral Infectivity

National Institutes of Health

Grant: 3R01AI146779-01S1

Epitope focusing to the receptor binding motif for a universal coronavirus vaccine

European Commission

Grant: 730964

European Vaccine Research and Development Infrastructure

French National Research Agency (ANR)

Grant: ANR-11-INBS-0008

National Institutes of Health

Grant: 3T32GM007753-41S1

Medical Scientist Training Program

Fondation pour la Recherche Médicale

Amicus Therapeutics

Biogen

Broad Institute

Centers for Disease Control and Prevention

Fundación Alfonso Martín Escudero

George Mason University

ADC Foundation

Bill and Melinda Gates Foundation

FWCI

10.28

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.chom.2021.08.002

publisherhttps://doi.org/10.1016/j.chom.2021.08.002

publisherhttps://api.elsevier.com/content/article/PII:S1931312821003784?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1931312821003784?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34428428

Fields of Study

Virus-based gene therapy researchSARS-CoV-2 and COVID-19 ResearchCAR-T cell therapy research0301 basic medicine03 medical and health sciences

MeSH Terms

Immunogenicity, VaccineCOVID-19SARS-CoV-2COVID-19 VaccinesDependovirusAnimalsAntibodies, ViralFemaleHumansImmunologic MemoryMacaca fascicularisMacaca mulattaMaleMice, Inbred BALB CMice, Inbred C57BLT-LymphocytesVaccinationTransgenesViral LoadMiceAntibodies, NeutralizingSpike Glycoprotein, Coronavirus

Keywords

ImmunogenicityVirologyBiologyPandemicNeutralizing antibodyImmunizationViral vectorImmunityCoronavirus disease 2019 (COVID-19)Vector (molecular biology)ImmunologyGenetic enhancementMemory T cellComputational biologyAntibodyRecombinant DNAGeneVirusImmune systemMedicineT cellGeneticsDiseaseInfectious disease (medical specialty)VaccineAdeno-associated virusAAVDurabilitySingle DoseViral ChallengeCovid-19Sars-cov-2Room-Temperature StableMaleCOVID-19 VaccinesT-LymphocytesAntibodies, ViralArticleMiceImmunogenicity, VaccineAnimalsHumansTransgenesMice, Inbred BALB CDependovirusAntibodies, NeutralizingMacaca mulatta[SDV] Life Sciences [q-bio]Mice, Inbred C57BLMacaca fascicularisSpike Glycoprotein, CoronavirusFemaleImmunologic Memory

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF

10.6084/m9.figshare.25698182.v1figshare

Additional file 1 of Analysis of the impact of pluronic acid on the thermal stability and infectivity of AAV6.2FF

10.6084/m9.figshare.25698182figshare