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Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers

Cell Host & Microbe(2021)10.1016/j.chom.2021.12.010Source: DataRank Database

Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers is a research paper published in Cell Host & Microbe (2021). On theSindex it has a DataRank of 1.8. It has been cited 63 times, with 49 citing works in its 1-hop citation network.

N/A

1.8DataRank · unranked

Scored on demand from live citation data

Open Access63 citations · 49 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 2.84)OA: bronzeTopics (61)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 35%Citation Network 65%

Base Score Contribution

0.624

From this paper's citation signal

Citation Network Contribution

1.2

From 34 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 49 citers.

Germline variants of IGHV3-53 / V3-66 are determinants of antibody responses to the BNT162b2 mRNA COVID-19 vaccine
Journal of Infection20229 citations9 referencesContributes 0.256
Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant
Immunity202252 citations40 referencesContributes 0.099
Breakthrough infection elicits hypermutated IGHV3-53/3-66 public antibodies with broad and potent neutralizing activity against SARS-CoV-2 variants including the emerging EG.5 lineages
PLoS Pathogens202333 citations45 referencesContributes 0.078
Discovery and characterization of SARS-CoV-2 reactive and neutralizing antibodies from humanized CAMouseHG mice through rapid hybridoma screening and high-throughput single-cell V(D)J sequencing
Frontiers in Immunology202218 citations43 referencesContributes 0.068
Potent NTD-Targeting Neutralizing Antibodies against SARS-CoV-2 Selected from a Synthetic Immune System
Vaccines202310 citations40 referencesContributes 0.060

Authors (27)

Chengcheng Fan ORCID,Marie Wunsch ORCID,Nareshkumar Poopalasingam ORCID,Matthijs Meijers ORCID,Christoph Kreer ORCID

Live enrichment

PubMed:34973165 OpenAlex:https://openalex.org/W4200119464

European Research Council

Grant: E RC-StG639961

Deutsches Zentrum für Infektionsforschung

Grant: CRC1279

Deutsche Forschungsgemeinschaft

Grant: 01KX2021

Deutsche Forschungsgemeinschaft

Grant: CRC1310

National Institutes of Health

Grant: 1P01AI138938-S1

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

European Commission

Grant: 639961

Antibody-Mediated Therapy of HIV-1 Infection

National Institutes of Health

Grant: 1P01AI138938-01

Epitope-focused vaccine strategies against Zika virus

FWCI

2.84

Citation Percentile

0.9%

Influential Citations

Citation Trend

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1931312821005813/pdf

BRONZEhttp://www.cell.com/article/S1931312821005813/pdf

publisherhttp://www.cell.com/article/S1931312821005813/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1931312821005813?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1931312821005813?httpAccept=text/plain

Fields of Study

SARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologyAnimal Virus Infections StudiesMedicine0301 basic medicine03 medical and health sciences

MeSH Terms

Broadly Neutralizing AntibodiesCOVID-19SARS-CoV-2AnimalsAntibodies, MonoclonalAntibodies, ViralCells, CulturedChlorocebus aethiopsCross ReactionsFemaleHumansMaleMiddle AgedNeutralization TestsVero CellsHEK293 CellsSpike Glycoprotein, Coronavirus

Keywords

AntibodyMonoclonal antibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BiologyCoronavirus disease 2019 (COVID-19)VirologyNeutralizationNeutralizing antibodyAntibody response2019-20 coronavirus outbreakImmunologyMedicineMale570610emerging variantsCross Reactionsvariants of concernAntibodies, ViralMicrobiologyArticleultrapotent monoclonal antibodiesNeutralization TestsChlorocebus aethiopsAnimalsHumansVero CellsCells, CulturedSARS-CoV-2broadly neutralizing antibodiesAntibodies, MonoclonalCOVID-19Middle AgedHEK293 CellsSpike Glycoprotein, Coronaviruscryo-EMParasitologyFemale

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being