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Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission

Cell Host & Microbe(2022)10.1016/j.chom.2022.01.006Source: DataRank Database

Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission is a research paper published in Cell Host & Microbe (2022). On theSindex it has a DataRank of 5.8. It has been cited 197 times, with 183 citing works in its 1-hop citation network.

N/A

5.8DataRank · unranked

Scored on demand from live citation data

Open Access197 citations · 183 citing works in its network

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Linked data & code

bioproject gen cellosaurus pxd doi pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (29 grants)Impact (FWCI 18.07)OA: bronzeTopics (55)IDs (PubMed, PMC, OpenAlex)Annotations (6)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 14%Citation Network 86%

Base Score Contribution

0.793

From this paper's citation signal

Citation Network Contribution

5.0

From 153 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 183 citers.

The SARS‐CoV‐2 omicron wave is indicating the end of the pandemic phase but the COVID‐19 will continue
Journal of Medical Virology202263 citations23 referencesContributes 0.181
Replication of SARS-CoV-2 Omicron BA.2 variant in ex vivo cultures of the human upper and lower respiratory tract
EBioMedicine202294 citations28 referencesContributes 0.163
Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant
Cell Reports2022393 citations44 referencesContributes 0.136
Intrinsic furin-mediated cleavability of the spike S1/S2 site from SARS-CoV-2 variant B.1.1.529 (Omicron)
bioRxiv (Cold Spring Harbor Laboratory)202235 citations29 referencesContributes 0.124
Viral isolation allows characterization of early samples of SARS-CoV-2 lineage B1.1.33 with unique mutations (S: H655Y and T63N) circulating in Southern Brazil in 2020
Brazilian Journal of Microbiology20223 citations12 referencesContributes 0.116

Authors (29)

Ana S. Gonzalez‐Reiche ORCID,Sadaf Aslam ORCID,Ignacio Mena ORCID,Manon Laporte ORCID,Rebecca L. Pearl ORCID

Live enrichment

PubMed:35150638 PMC:PMC8776496 OpenAlex:https://openalex.org/W4205998015

NCI

Grant: U54CA260560

Open Philanthropy Project

Grant: 2020-215611 (5384

Department of Homeland Security

Grant: HSHQDC 16-A-B0006

NIAID

Grant: U19AI135972

NIAID

Grant: U19AI142733

NIAID

Grant: 75N93021C00014

NIGMS

Grant: P20GM130448

DARPA

Grant: HR0011-19-2-0020

U.S. Department of Defense

Grant: MiA2

U.S. Department of Defense

Grant: MiA1

NIH HHS

Grant: S10 OD030463

NIAID NIH HHS

Grant: U19 AI135990

NIH HHS

Grant: S10 OD026880

NIAID NIH HHS

Grant: HHSN272201400006C

National Institutes of Health

Grant: 3U54CA260560-02S2

Vulnerability of SARS- CoV-2 Infection in Lung Cancer Based on Serological Antibody Analyses

National Institutes of Health

Grant: 3U19AI142733-04S1

Modulation of Lung Immune Responses to Viral Infection

National Institutes of Health

Grant: 5U19AI135972-04

Fluomics: The Next Generation

National Institutes of Health

Grant: 1P20GM130448-01A1

Center on Emerging and Zoonotic Infectious Diseases

National Institutes of Health

Grant: 5U19AI135990-03

HPMI: Host Pathogen Mapping Initiative

Belgian American Educational Foundation

JPB Foundation

Merck

Pfizer

F. Hoffmann-La Roche

Icahn School of Medicine at Mount Sinai

National Institutes of Health

National Center for Emerging and Zoonotic Infectious Diseases

Tenax Therapeutics

Vir Biotechnology

FWCI

18.07

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1931312822000427/pdf

publisherhttp://www.cell.com/article/S1931312822000427/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1931312822000427?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1931312822000427?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.chom.2022.01.006

Fields of Study

SARS-CoV-2 and COVID-19 ResearchViral gastroenteritis research and epidemiologySARS-CoV-2 detection and testing0301 basic medicine03 medical and health sciencesCOVID-19HumansMutationSARS-CoV-2Spike Glycoprotein, CoronavirusSARS-CoV-2 variants

MeSH Terms

COVID-19SARS-CoV-2HumansMutationSpike Glycoprotein, Coronavirus

Keywords

BiologyHamsterSpike (software development)VirologyVirusGeneticsCleavage (geology)Viral replicationMutationTransmission (telecommunications)GeneMolecular biologyFusionGammaSyncytia FormationSars-cov-2Spike CleavageVariants Of ConcernOmicronH655y Mutation570CoronavirusesImmunology610MicrobiologyArticle2.2 Factors relating to the physical environmentHumansBiomedical and Clinical SciencesCOVID-19Medical microbiologySpike GlycoproteinCoronavirusEmerging Infectious DiseasesInfectious DiseasesGood Health and Well BeingBiochemistry and cell biologySpike Glycoprotein, CoronavirusInfection

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being