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Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development

Cell Host & Microbe(2025)10.1016/j.chom.2025.01.004Source: DataRank Database

Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development is a research paper published in Cell Host & Microbe (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (12 grants)Impact (FWCI 1.80)OA: hybridTopics (58)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (38)

Marius Zeeb ORCID,Peter Rusert ORCID,Chloé Pasin ORCID,Jennifer L. Mamrosh ORCID,Samuel Mundia Kariuki ORCID

Live enrichment

PubMed:39909038 OpenAlex:https://openalex.org/W4407135279

Bill and Melinda Gates Foundation

Grant: INV-036842

National Research Council

Grant: 98341

Novartis Foundation for Medical-Biological Research

Grant: 23B127

Swiss National Science Foundation

Grant: 3147308_201266

Swiss National Science Foundation

Grant: 201369

Swiss National Science Foundation

Grant: 148522

Swiss National Science Foundation

Grant: 201266

Imprinting broadly neutralizing antibody responses to HIV-1

Universität Zürich

National Institutes of Health

National Research Foundation

Novartis Foundation

South African Medical Research Council

FWCI

1.80

Citation Percentile

0.8%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.chom.2025.01.004

publisherhttps://doi.org/10.1016/j.chom.2025.01.004

publisherhttps://api.elsevier.com/content/article/PII:S1931312825000228?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1931312825000228?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39909038

Fields of Study

HIV Research and TreatmentHIV/AIDS drug development and treatmentHIV-related health complications and treatments0301 basic medicine03 medical and health sciencesHIV-1HumansCysteineHIV AntibodiesHIV InfectionsAntibodies, NeutralizingEpitopesenv Gene Products, Human Immunodeficiency VirusCross ReactionsHIV Envelope Protein gp120

MeSH Terms

EpitopesCross ReactionsCysteineHumansHIV AntibodiesHIV-1HIV InfectionsHIV Envelope Protein gp120AIDS Vaccinesenv Gene Products, Human Immunodeficiency VirusImmune EvasionAntibodies, Neutralizing

Keywords

BiologyNeutralizationLink (geometry)CysteineEnvelope (radar)Variable (mathematics)Human immunodeficiency virus (HIV)VirologyComputational biologyGeneticsBiochemistryVirusCombinatoricsComputer scienceEnzymeEnvelope glycoproteinHiv VaccineBroadly Neutralizing AntibodiesV1v2Elite NeutralizersEnv Stabilizationenv Gene Products, Human Immunodeficiency VirusHIV InfectionsHIV AntibodiesCross ReactionsHIV Envelope Protein gp120Antibodies, NeutralizingEpitopesHIV-1/immunology; HIV-1/genetics; Humans; Cysteine/genetics; Cysteine/immunology; Cysteine/chemistry; HIV Antibodies/immunology; HIV Infections/immunology; HIV Infections/virology; Antibodies, Neutralizing/immunology; Epitopes/immunology; Epitopes/genetics; env Gene Products, Human Immunodeficiency Virus/immunology; env Gene Products, Human Immunodeficiency Virus/genetics; env Gene Products, Human Immunodeficiency Virus/chemistry; Cross Reactions; HIV Envelope Protein gp120/immunology; HIV Envelope Protein gp120/genetics; HIV Envelope Protein gp120/chemistry; Env stabilization; HIV vaccine; V1V2; broadly neutralizing antibodies; elite neutralizers; envelope glycoproteinHIV-1Humans

Sustainable Development Goals

SDG 0: Zero hunger