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A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation

Cell Host & Microbe(2025)10.1016/j.chom.2025.09.010Source: DataRank Database

A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation is a research paper published in Cell Host & Microbe (2025). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)OA: greenTopics (52)IDs (PubMed)

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Accessible (1/2)

Open Access

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Reusable (0/3)

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Authors (19)

Rocco Latorre ORCID,Kristýna Blažková ORCID,Hannah M. Wood ORCID,Dane D. Jensen ORCID,Nayab Shakil

Live enrichment

PubMed:41015045

Fonds der Chemischen Industrie

Grant: EXC 2051

Fonds der Chemischen Industrie

Grant: 528114058

Fonds der Chemischen Industrie

Grant: 390713860

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01 DK130293

National Institutes of Health

Grant: T32 GM120007

National Institutes of Health

Grant: R01 NS125413

National Institutes of Health

Grant: 1S10OD030473

Deutsche Forschungsgemeinschaft

Grant: 450273105

Canadian Institutes of Health Research

Grant: 166053

Canadian Institutes of Health Research

Grant: unidentified

unidentified

greenLicense: Elsevier TDM

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12919672/

publisherhttps://api.elsevier.com/content/article/PII:S1931312825003762?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1931312825003762?httpAccept=text/plain

https://doi.org/10.1016/j.chom.2025.09.010

https://pubmed.ncbi.nlm.nih.gov/41015045

Fields of Study

0301 basic medicine03 medical and health sciencesReceptor, PAR-2Bacteroides fragilisAnimalsMiceHumansGastrointestinal MicrobiomeInflammationMice, Inbred C57BLInflammatory Bowel DiseasesDisease Models, AnimalIrritable Bowel SyndromeBacterial ProteinsSerine ProteasesMale

MeSH Terms

Receptor, PAR-2Bacteroides fragilisAnimalsMiceHumansGastrointestinal MicrobiomeInflammationMice, Inbred C57BLInflammatory Bowel DiseasesDisease Models, AnimalIrritable Bowel SyndromeBacterial ProteinsSerine ProteasesMale

Keywords

InflammationMaleInflammatory Bowel DiseasesArticleGastrointestinal MicrobiomeBacteroides fragilisMice, Inbred C57BLIrritable Bowel SyndromeMiceDisease Models, AnimalBacterial ProteinsReceptor, PAR-2AnimalsHumansSerine Proteasesactivity-based probegut microbiotainflammatory bowel diseaseintestinal organoidspain signalingproteaseprotease-activated receptors