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Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation

Cell Metabolism(2020)10.1016/j.cmet.2020.10.002Source: DataRank Database

Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation is a research paper published in Cell Metabolism (2020). On theSindex it has a DataRank of 0. It has been cited 96 times.

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Open Access96 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (12 grants)Impact (FWCI 3.11)OA: bronzeTopics (64)Linked Datasets (10)DataCite Reuse (10)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (8)

Yi Xu ORCID,Wenyun Lu ORCID,Jonathan M. Ghergurovich ORCID,Lili Guo ORCID,Ian A. Blair ORCID

Live enrichment

PubMed:33159852 PMC:PMC7846267 OpenAlex:https://openalex.org/W3097928186

NCI NIH HHS

Grant: T32 CA115299

NCI NIH HHS

Grant: R01 CA243520

NCI NIH HHS

Grant: R01 CA182675

NCI NIH HHS

Grant: R01 CA235760

NCI NIH HHS

Grant: R50 CA211437

NCI NIH HHS

Grant: R01 CA184867

NIEHS NIH HHS

Grant: P30 ES013508

National Institutes of Health

Grant: 5R01CA182675-02

p53 and tumor cell metabolism

National Institutes of Health

Grant: 1R01CA184867-01

Role of p53 family proteins in glucose metabolism

National Institutes of Health

Grant: 5R01CA243520-03

A novel protein quality control system and its role in tumorigenesis

National Institutes of Health

Grant: 5R50CA211437-04

Revealing cancer metabolism via mass spectrometry and isotope tracers

National Institutes of Health

FWCI

3.11

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1550413120305350/pdf

publisherhttp://www.cell.com/article/S1550413120305350/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1550413120305350?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1550413120305350?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cmet.2020.10.002

Fields of Study

Cancer, Hypoxia, and MetabolismPancreatic function and diabetesCancer Research and Treatments0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsAntioxidantsCell Transformation, NeoplasticCells, CulturedGlucosephosphate DehydrogenaseHumansMaleMiceMice, NudeNucleotidesUp-Regulation

MeSH Terms

AnimalsAntioxidantsCell Transformation, NeoplasticCells, CulturedGlucosephosphate DehydrogenaseHumansMaleMice, NudeNucleotidesUp-RegulationMice

Keywords

Downregulation and upregulationNAD+ kinaseNucleotideTransformation (genetics)BiologyCell growthKinaseDehydrogenaseCell biologyBiochemistryMalignant transformationCancer cellEnzymeGeneCancerGeneticsAntioxidantsNAD kinaseG6PDNADPHNucleosidesPentose phosphate pathwayCancer MetabolismRedox RegulationOncogenic TransformationNucleotide SynthesisMaleNucleotidesMice, NudeGlucosephosphate DehydrogenaseUp-RegulationMiceCell Transformation, NeoplasticAnimalsHumansCells, Cultured

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Additional file 2 of SLC6A8-mediated intracellular creatine accumulation enhances hypoxic breast cancer cell survival via ameliorating oxidative stress

10.6084/m9.figshare.14600488figshare

Additional file 1 of SLC6A8-mediated intracellular creatine accumulation enhances hypoxic breast cancer cell survival via ameliorating oxidative stress

10.6084/m9.figshare.14600485.v1figshare

Additional file 1 of SLC6A8-mediated intracellular creatine accumulation enhances hypoxic breast cancer cell survival via ameliorating oxidative stress

10.6084/m9.figshare.14600485figshare

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Additional file 1 of A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC

10.6084/m9.figshare.26655625figshare

Additional file 3 of A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC

10.6084/m9.figshare.26655631.v1figshare

Additional file 3 of A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC

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Additional file 2 of A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC

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Additional file 2 of A feedback loop of PPP and PI3K/AKT signal pathway drives regorafenib-resistance in HCC