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Gang of 3: How the Krebs cycle-linked metabolites itaconate, succinate, and fumarate regulate macrophages and inflammation

Cell Metabolism(2025)10.1016/j.cmet.2025.03.004Source: DataRank Database

Gang of 3: How the Krebs cycle-linked metabolites itaconate, succinate, and fumarate regulate macrophages and inflammation is a research paper published in Cell Metabolism (2025). On theSindex it has a DataRank of 0.694. It has been cited 101 times.

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0.694DataRank · unranked

Scored on demand from live citation data

101 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 30.95)OA: hybridTopics (34)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.694

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (2)

Luke A.J. O’Neill,Eva M. Pålsson-McDermott

Live enrichment

PubMed:40169002 OpenAlex:https://openalex.org/W4409087851

Taighde Éireann – Research Ireland

Grant: 19/FFP/6507

Exploring Itaconate as a Critical Immunometabolite in Inflammation

European Research Council

Grant: 834370

Metabolic crosstalk in the regulation of inflammation

Irish Research eLibrary

Grant: unidentified

unidentified

European Research Council

FWCI

30.95

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.cmet.2025.03.004

publisherhttps://doi.org/10.1016/j.cmet.2025.03.004

publisherhttps://api.elsevier.com/content/article/PII:S155041312500107X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S155041312500107X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40169002

Fields of Study

Tryptophan and brain disordersCytokine Signaling Pathways and InteractionsEndoplasmic Reticulum Stress and Disease03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsCitric Acid CycleFumaratesHumansInflammationMacrophagesSuccinatesSuccinic Acid

Keywords

InflammationCitric acid cycleChemistryDimethyl fumarateCell biologyBiochemistryMetabolismBiologyMicrobiologyImmunologyKrebs CycleTherapeutic TargetsEtcImmunometabolismImmunometabolitesFumaratesMacrophagesSuccinic AcidHumansAnimalsSuccinates