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Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

Developmental Cell(2021)10.1016/j.devcel.2021.03.032Source: DataRank Database

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C is a research paper published in Developmental Cell (2021). On theSindex it has a DataRank of 0. It has been cited 68 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access68 citations

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Linked data & code

gen uniprot

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 6.51)OA: bronzeTopics (65)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Sunan Li ORCID,Tamar Farfel‐Becker,Ning Huang ORCID,Tao Sun ORCID,Yuxiang Xie ORCID

Live enrichment

PubMed:33878344 PMC:PMC8137671 OpenAlex:https://openalex.org/W3155246752

National Institutes of Health

Grant: ZIA NS002946

National Institutes of Health

Grant: ZIA NS003029

Intramural NIH HHS

Grant: Z01 NS003029

Wellcome Trust

Grant: 202834/Z/16/Z

Intramural NIH HHS

Grant: Z01 NS002946

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 1ZIANS003029-05

Mitochondrial transport: impact on synaptic transmission and neurodegeneration

National Institutes of Health

Grant: 1ZIANS002946-14

Regulation of synaptic transmission and autophagy-lysosomal function

National Institutes of Health

FWCI

6.51

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S1534580721003075/pdf

publisherhttp://www.cell.com/article/S1534580721003075/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1534580721003075?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1534580721003075?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.devcel.2021.03.032

Fields of Study

Lysosomal Storage Disorders ResearchAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolism0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AutophagosomesNiemann-Pick C1 ProteinAnimalsAutophagyAxonsBiological TransportCholesterolIntracellular MembranesLipidsLysosomesMice, Inbred BALB CMuscular DystrophiesStress, PhysiologicalKinesinsCell DeathGTP PhosphohydrolasesCytoplasmic VesiclesMiceNiemann-Pick Disease, Type C

Keywords

LysosomeAutophagyBiologyCell biologyNiemann–Pick diseaseTFEBEndocytic cycleNiemann–Pick disease, type CAutophagosomeAxoplasmic transportLysosomal storage diseaseNeuroscienceEndocytosisCellBiochemistryCholesterolLipidKinesinNeurodegenerationAxonal TransportLysosomal Storage DisorderNiemann-pick Disease Type CAxonal DystrophyMice, Inbred BALB CCell DeathCytoplasmic VesiclesAutophagosomesKinesinsBiological TransportNiemann-Pick Disease, Type CIntracellular MembranesLipidsAxonsMuscular DystrophiesGTP PhosphohydrolasesMiceNiemann-Pick C1 ProteinStress, PhysiologicalAnimalsLysosomes

Sustainable Development Goals

SDG 0: Good health and well-being