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FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma

Developmental Cell(2024)10.1016/j.devcel.2024.10.009Source: DataRank Database

FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma is a research paper published in Developmental Cell (2024). On theSindex it has a DataRank of 0.474. It has been cited 16 times, with 13 citing works in its 1-hop citation network.

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0.474DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access16 citations · 13 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE247855

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 2.63)OA: greenTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 90%Citation Network 10%

Base Score Contribution

0.425

From this paper's citation signal

Citation Network Contribution

0.0487

From 7 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 13 citers.

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Biochimica et Biophysica Acta (BBA) - Reviews on Cancer20259 citations167 referencesContributes 0.014
CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1
Molecular Cancer20261 citations78 referencesContributes 0.009
A small-molecule compound cocktail for tumor reprogramming therapy for breast cancer
International Immunopharmacology20251 citations80 referencesContributes 0.009
Epigenetic reprogramming as the nexus of cancer stemness and therapy resistance: implications for biomarker discovery
Discover Oncology202510 citations279 referencesContributes 0.009
Mechanisms and implications of epithelial cell plasticity in the bladder
Nature Reviews Urology20253 citations185 referencesContributes 0.007

Authors (10)

Walter A. Orellana ORCID,Emily Wilson ORCID,Timothy J. Parnell ORCID,Gabriela Fort,Pengshu Fang ORCID

Live enrichment

PubMed:39515329 PMC:PMC11794038 OpenAlex:https://openalex.org/W4404137622

National Institutes of Health

Grant: R01CA237404

National Institutes of Health

Grant: P30CA042014

American Lung Association in Georgia

Grant: LCD-821670

National Center for Research Resources

Grant: 1S20RR026802-1

National Cancer Institute

Grant: R01CA212415

National Cancer Institute

Grant: R01CA240317

National Cancer Institute

Grant: F31CA275266

National Cancer Institute

Grant: F31CA275328

National Cancer Institute

Grant: T32GM141848

NCRR NIH HHS

Grant: S10 RR026802

Huntsman Cancer Foundation

Department of Pathology, Northwestern University

University of Utah

American Lung Association

Huntsman Cancer Institute, University of Utah

FWCI

2.63

Citation Percentile

0.9%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11794038/

publisherhttps://api.elsevier.com/content/article/PII:S1534580724006282?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1534580724006282?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.devcel.2024.10.009

Fields of Study

Epigenetics and DNA MethylationFOXO transcription factor regulationRNA modifications and cancerHepatocyte Nuclear Factor 3-alphaAnimalsHepatocyte Nuclear Factor 3-betaLung NeoplasmsHumansMiceCell LineageAdenocarcinoma of LungDNA MethylationThyroid Nuclear Factor 1Epigenesis, GeneticAdenocarcinomaGene Expression Regulation, NeoplasticEpigenomicsChromatinCellular Reprogramming

MeSH Terms

Thyroid Nuclear Factor 1Adenocarcinoma of LungAdenocarcinomaAnimalsChromatinHistonesHumansLung NeoplasmsGene Expression Regulation, NeoplasticCell LineageDNA MethylationEpigenesis, GeneticMiceHepatocyte Nuclear Factor 3-alphaHepatocyte Nuclear Factor 3-betaEpigenomicsCellular Reprogramming

Keywords

BiologyReprogrammingEpigenomicsFOXA1Lineage (genetic)AdenocarcinomaGeneticsCancer researchComputational biologyCancerGeneTranscription factorDNA methylationLung adenocarcinomaepigenetic reprogrammingFoxa1/2Tet2/3Cancer Lineage Switching/plasticity