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AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth

Developmental Cell(2025)10.1016/j.devcel.2025.05.008Source: DataRank Database

AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth is a research paper published in Developmental Cell (2025). On theSindex it has a DataRank of 0. It has been cited 5 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (12 grants)Impact (FWCI 2.43)OA: greenTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

S. Lapp,Krystle C. Kalafut ORCID,Madi Y. Cissé ORCID,Jong Shin ORCID,Benjamin Stefadu

Live enrichment

PubMed:40480230 PMC:PMC12258181 OpenAlex:https://openalex.org/W4411059628

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: F31-DK128873

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: T32-DK128781

National Institutes of Health National Cancer Institute

Grant: R35-CA197459

National Institutes of Health National Cancer Institute

Grant: P01-CA120964

Damon Runyon Cancer Research Foundation

Grant: 2443-21

NICHD NIH HHS

Grant: P50 HD105351

NIDDK NIH HHS

Grant: F31 DK128873

NCI NIH HHS

Grant: P01 CA120964

NCI NIH HHS

Grant: R35 CA197459

NIDDK NIH HHS

Grant: T32 DK128781

National Institutes of Health

Glenn Foundation for Medical Research

FWCI

2.43

Citation Percentile

0.9%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12258181/

publisherhttps://api.elsevier.com/content/article/PII:S1534580725003193?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1534580725003193?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.devcel.2025.05.008

Fields of Study

PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex ResearchPolyamine Metabolism and ApplicationsAnimalsTuberous Sclerosis Complex 2 ProteinMechanistic Target of Rapamycin Complex 1Proto-Oncogene Proteins c-aktPhosphorylationSignal TransductionMiceTumor Suppressor ProteinsTOR Serine-Threonine KinasesMultiprotein ComplexesOrgan SpecificityMuscle, SkeletalHumans

MeSH Terms

Mechanistic Target of Rapamycin Complex 1Tuberous Sclerosis Complex 2 ProteinAnimalsHumansOrgan SpecificityPhosphorylationSignal TransductionMuscle, SkeletalTumor Suppressor ProteinsMultiprotein ComplexesProto-Oncogene Proteins c-aktMiceTOR Serine-Threonine Kinases

Keywords

BiologymTORC1PhosphorylationStimulus (psychology)Cell biologyProtein kinase BTSC2Signal transductionCancer researchPI3K/AKT/mTOR pathwayNeuronsInsulinLysosomeFeedingMyotubesPI3KPhosphoinositide 3-kinaseMicrocephalyLean MassRheb