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Impact of sex and pregnancy on hepatic CYP3A4 expression and activity in a humanized mouse model

Drug Metabolism and Disposition(2024)10.1016/j.dmd.2024.100025Source: DataRank Database

Impact of sex and pregnancy on hepatic CYP3A4 expression and activity in a humanized mouse model is a research paper published in Drug Metabolism and Disposition (2024). On theSindex it has a DataRank of 0. It has been cited 8 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 2.82)OA: greenTopics (52)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Taryn A. Miner ORCID,Valeria Laboy Collazo,Joseph T. Grieco,John K. Fallon ORCID,Klarissa D. Jackson ORCID

Live enrichment

PubMed:40023573 PMC:PMC12105745 OpenAlex:https://openalex.org/W4404850795

NICHD NIH HHS

Grant: R01 HD098742

NIEHS NIH HHS

Grant: P30 ES010126

NIEHS NIH HHS

Grant: P42 ES031007

NCRR NIH HHS

Grant: S10 RR024595

NIGMS NIH HHS

Grant: R35 GM143044

FWCI

2.82

Citation Percentile

0.9%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12105745/pdf/main.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0090955624148751?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624148751?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12105745

Fields of Study

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsEicosanoids and Hypertension PharmacologyCytochrome P-450 CYP3AAnimalsFemalePregnancyMaleMiceHumansLiverMicrosomes, LiverPregnane X ReceptorConstitutive Androstane ReceptorMice, TransgenicSex FactorsReceptors, Cytoplasmic and NuclearSex CharacteristicsMidazolam

MeSH Terms

Pregnane X ReceptorConstitutive Androstane ReceptorAnimalsFemaleHumansLiverMaleMice, TransgenicMicrosomes, LiverMidazolamPregnancyReceptors, SteroidRNA, MessengerSex CharacteristicsSex FactorsReceptors, Cytoplasmic and NuclearMiceCytochrome P-450 CYP3A

Keywords

CYP3A4Humanized mousePregnancyBiologyDrug metabolismCytochrome P450AndrologyEndocrinologyMedicineMetabolismGeneticsIn vivoSexTargeted Proteomics4Β-hydroxycholesterol