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Treatment of human cells with 5-aza-dC induces formation of PARP1-DNA covalent adducts at genomic regions targeted by DNMT1

DNA repair(2020)10.1016/j.dnarep.2020.102977Source: DataRank Database

Treatment of human cells with 5-aza-dC induces formation of PARP1-DNA covalent adducts at genomic regions targeted by DNMT1 is a research paper published in DNA repair (2020). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.30)OA: greenTopics (63)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Yinbo Zhang ORCID,Nancy Maizels ORCID,Kostantin Kiianitsa ORCID

Live enrichment

PubMed:33039802 PMC:PMC7669653 OpenAlex:https://openalex.org/W3091214896

NCI NIH HHS

Grant: R21 CA194876

NCI NIH HHS

Grant: P01 CA077852

NCI NIH HHS

Grant: R01 CA183967

National Institutes of Health

Grant: 5R01CA183967-02

Genomic Instability at DNA Nicks

National Institutes of Health

Grant: 2P01CA077852-16A1

Bioinformatics/statistical support

National Institutes of Health

FWCI

0.30

Citation Percentile

0.6%

Citation Trend

2021

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7669653

publisherhttps://api.elsevier.com/content/article/PII:S1568786420302263?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1568786420302263?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.dnarep.2020.102977

Fields of Study

PARP inhibition in cancer therapyDNA Repair MechanismsEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciencesAntimetabolites, AntineoplasticAzacitidineCells, CulturedCpG IslandsDNADNA (Cytosine-5-)-Methyltransferase 1DNA AdductsDNA MethylationHematologic NeoplasmsHumansK562 CellsPoly (ADP-Ribose) Polymerase-1

MeSH Terms

Poly (ADP-Ribose) Polymerase-1DNA (Cytosine-5-)-Methyltransferase 1Antimetabolites, AntineoplasticAzacitidineCells, CulturedDNAHumansDNA AdductsCpG IslandsDNA MethylationHematologic NeoplasmsK562 Cells

Keywords

AdductBiologyDNAPARP1Molecular biologyDNMT1DNA damageApoptosisDNA methylationDNA methyltransferaseCancer researchBiochemistryChemistryMethylationMethyltransferasePoly ADP ribose polymerasePolymeraseGeneGene expression5-methylcytosineDecitabineDna-protein CrosslinkCg IslandRadar EnrichmentDNA (Cytosine-5-)-Methyltransferase 1Antimetabolites, AntineoplasticPoly (ADP-Ribose) Polymerase-1DNA AdductsHematologic NeoplasmsAzacitidineHumansCpG IslandsK562 CellsCells, Cultured

Sustainable Development Goals

SDG 0: Good health and well-being

Treatment of human cells with 5-aza-dC induces formation of PARP1-DNA covalent adducts at genomic regions targeted by DNMT1

FAIR Checklist

Authors (3)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)