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Wip1 phosphatase activator QGC-8–52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells

Drug Resistance Updates(2024)10.1016/j.drup.2024.101196Source: DataRank Database

Wip1 phosphatase activator QGC-8–52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells is a research paper published in Drug Resistance Updates (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

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6 citations

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Enrichment:Funding (9 grants)OA: closedTopics (22)IDs (PubMed)

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Reusable (0/3)

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Authors (10)

Xiaoxiao Ge,Xiao-xiao Ge,Jieqing Li ORCID,Kun Wang ORCID,Qiao‐Hong Chen ORCID

Live enrichment

PubMed:39787991

National Natural Science Foundation of China

Grant: 82173263

American Cancer Society

Grant: G003PP07

National Cancer Institute

Grant: 9 SC1 GM135050-05

National Cancer Institute

Grant: G0812D05

National Cancer Institute

Grant: SC1CA200517

National Cancer Institute

Grant: G0814C11

National Institute on Minority Health and Health Disparities

Grant: U54MD007598

Program for Education and Research in Biotechnology, California State University

National Institutes of Health

closedLicense: https://doi.org/10.15223/policy-004

publisherhttps://api.elsevier.com/content/article/PII:S1368764624001547?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1368764624001547?httpAccept=text/plain

MeSH Terms

Cell Line, TumorAnimalsHumansMiceBreast NeoplasmsAntineoplastic AgentsXenograft Model Antitumor AssaysSignal TransductionApoptosisGene Expression Regulation, NeoplasticPhosphorylationDrug Resistance, NeoplasmFemaleTumor Suppressor Protein p53Phosphoprotein PhosphatasesProtein Phosphatase 2CForkhead Box Protein O3

Keywords

Breast cancerTRAILdephosphorylationFoxo3aWip1

Wip1 phosphatase activator QGC-8–52 specifically sensitizes p53-negative cancer cells to chemotherapy while protecting normal cells

FAIR Checklist

Authors (10)

Funding (9 grants)

Open Access

Topics