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S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis

EBioMedicine(2020)10.1016/j.ebiom.2020.102898Source: DataRank Database

S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis is a research paper published in EBioMedicine (2020). On theSindex it has a DataRank of 0. It has been cited 33 times.

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Open Access33 citations

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Enrichment:Funding (7 grants)OA: goldTopics (54)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC)Annotations (2)SDGs (1)

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Context only (not used in score)

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Accessible (1/2)

Open Access

Interoperable (2/2)

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Authors (14)

Sören S. Hüttner ORCID,Kristin Ludwig,Nadine Krieg,Susann Hofmann,Nathalie H. Schröder ORCID

Live enrichment

PubMed:32711251 PMC:PMC7381498

Deutsche Forschungsgemeinschaft

Grant: RTG 1715

NIGMS NIH HHS

Grant: R01 GM043880

National Institutes of Health

Grant: 2R01GM043880-09

SPHINGOLIPID METABOLITE, SPHINGOSINE 1 PHOSPHATE

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

Center for Sepsis Control and Care

Astellas Pharma US

Gilead Sciences

goldLicense: CC BY NC ND

Europe_PMChttps://europepmc.org/articles/PMC7381498

Europe_PMChttps://europepmc.org/articles/PMC7381498?pdf=render

https://doi.org/10.1016/j.ebiom.2020.102898

http://www.thelancet.com/article/S2352396420302735/pdf

https://pubmed.ncbi.nlm.nih.gov/32711251

Fields of Study

03 medical and health sciences0302 clinical medicine

MeSH Terms

Cells, CulturedAnimalsHumansMiceSepsisDisease Models, AnimalEpirubicinAldehyde-LyasesExtracellular Signal-Regulated MAP Kinasesp38 Mitogen-Activated Protein KinasesPulmonary Surfactant-Associated Protein DTreatment OutcomeProspective StudiesRandom AllocationCell Membrane PermeabilityDown-RegulationAutophagyMucin-1Sphingosine-1-Phosphate Receptors

Keywords

LungCytokineLipopolysaccharidesphingosine 1-phosphateEpirubicinAutophagyAnthracyclineperitonitisEpithelial BarrierMedicine (General)Research paperCell Membrane PermeabilityDown-Regulationp38 Mitogen-Activated Protein KinasesGeneral Biochemistry, Genetics and Molecular BiologyMiceRandom AllocationR5-920SepsisAnimalsHumansProspective StudiesExtracellular Signal-Regulated MAP KinasesSphingosine-1-Phosphate ReceptorsCells, CulturedAldehyde-LyasesMucin-1RGeneral MedicinePulmonary Surfactant-Associated Protein DDisease Models, AnimalTreatment OutcomeMedicine

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation

10.6084/m9.figshare.26729989figshare

Additional file 1 of S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-κB and improving mitochondrial oxidative phosphorylation

10.6084/m9.figshare.26729989.v1figshare

S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis

FAIR Checklist

Authors (14)

Funding (7 grants)

Open Access

Topics

Linked Datasets (2)

Annotations (Europe PMC)