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Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia

EBioMedicine(2021)10.1016/j.ebiom.2021.103235Source: DataRank Database

Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia is a research paper published in EBioMedicine (2021). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 0.38)OA: goldTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (21)

Yoriko Saito ORCID,Eiryo Kawakami ORCID,Mari Hashimoto,Yuki Aoki ORCID,Rintaro Ono ORCID

Live enrichment

PubMed:33581643 PMC:PMC7878180 OpenAlex:https://openalex.org/W3127751772

NCI NIH HHS

Grant: P30 CA034196

RIKEN

Japan Agency for Medical Research and Development

Ministry of Education, Culture, Sports, Science and Technology

National Institutes of Health

FWCI

0.38

Citation Percentile

0.6%

Citation Trend

2023

2025

2026

goldLicense: cc-by

journalhttp://www.thelancet.com/article/S2352396421000281/pdf

publisherhttp://www.thelancet.com/article/S2352396421000281/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2352396421000281?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2352396421000281?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ebiom.2021.103235

Fields of Study

Acute Lymphoblastic Leukemia researchChronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia ResearchAnimalsAntineoplastic AgentsApoptosisBiomarkers, TumorCell Line, TumorDisease Models, AnimalDrug Resistance, NeoplasmDrug SynergismGene Expression ProfilingGene Expression Regulation, LeukemicGene RearrangementHistone-Lysine N-MethyltransferaseHumansImmunohistochemistryMiceMice, KnockoutMyeloid-Lymphoid Leukemia ProteinPyrimidinesPyrrolesSteroidsXenograft Model Antitumor Assays

MeSH Terms

AnimalsAntineoplastic AgentsDisease Models, AnimalDrug SynergismHumansImmunohistochemistryHistone-Lysine N-MethyltransferasePyrimidinesPyrrolesSteroidsBiomarkers, TumorGene RearrangementGene Expression Regulation, LeukemicApoptosisMice, KnockoutDrug Resistance, NeoplasmGene Expression ProfilingXenograft Model Antitumor AssaysCell Line, TumorMiceMyeloid-Lymphoid Leukemia Protein

Keywords

KinaseCancer researchApoptosisProtein-Serine-Threonine KinasesBiologyMedicineCell biologyGeneticsProtein kinase ALeukaemiaxenograftMllHumanized Mouse

Sustainable Development Goals

SDG 0: Good health and well-being

Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia

FAIR Checklist

Authors (21)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)