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Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity

EBioMedicine(2023)10.1016/j.ebiom.2023.104514Source: DataRank Database

Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity is a research paper published in EBioMedicine (2023). On theSindex it has a DataRank of 0. It has been cited 85 times.

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Open Access85 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 6.01)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Todd W. Dowrey ORCID,Carlos Villacorta-Martín ORCID,Monty Montano ORCID,Eric Reed ORCID,Anna C. Belkina ORCID

Live enrichment

PubMed:37005201 PMC:PMC10114155 OpenAlex:https://openalex.org/W4362466820

NIH HHS

Grant: S10 OD021587

NIA NIH HHS

Grant: UH3 AG064704

National Institute on Aging

Grant: U19AG023122

National Institute on Aging

Grant: P30 AG031679-10

NIA NIH HHS

Grant: P30 AG031679

NIA NIH HHS

Grant: UH2 AG064704

National Institutes of Health

Grant: 1UH2AG064704-01

Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategies

National Institutes of Health

Grant: 1S10OD021587-01A1

MoFlo Astrios EQ High Speed Cell Sorter

National Institutes of Health

Grant: 5U19AG023122-04

Consortium to Study the Genetics of Longevity

National Institutes of Health

Grant: 5P30AG031679-02

BU--WAGENAAR

FWCI

6.01

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.thelancet.com/article/S2352396423000798/pdf

publisherhttp://www.thelancet.com/article/S2352396423000798/pdf

journalhttps://doi.org/10.1016/j.ebiom.2023.104514

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37005201

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10114155

Fields of Study

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomicsImmune responses and vaccinations03 medical and health sciences0302 clinical medicine

MeSH Terms

AdultAgedAged, 80 and overAgingHumansLeukocytes, MononuclearLongevityMiddle AgedProtein Serine-Threonine KinasesApoptosis Regulatory ProteinsYoung Adult

Keywords

LongevityBiologyImmune systemPeripheral blood mononuclear cellTranscriptomeImmunosenescenceImmunologyGeneGeneticsGene expressionAgingSingle Cell Rna SequencingExtreme Human LongevityElite ImmunityAged, 80 and overAdultYoung AdultLeukocytes, MononuclearHumansMiddle AgedProtein Serine-Threonine KinasesApoptosis Regulatory ProteinsAged

Sustainable Development Goals

SDG 0: Good health and well-being