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A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals

EBioMedicine(2024)10.1016/j.ebiom.2024.105086Source: DataRank Database

A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals is a dataset published in EBioMedicine (2024). On theSindex it has a DataRank of 0.447, placing it in the top 42.1% of the data-sharing corpus. It has been cited 13 times, with 11 citing works in its 1-hop citation network.

Top 42%percentile

0.447DataRank

Ranks in the top 42% for downstream scientific impact

Data paper Open Access13 citations · 11 citing works in its network

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Linked data & code

Characterizing genetic pathways for tobacco use by sex and across the lifespan · University of California Office of the President

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DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 4.11)OA: goldTopics (77)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (1/3)

Dataset classification

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DataRank Breakdown

Base Score 89%Citation Network 11%

Base Score Contribution

0.396

From this paper's citation signal

Citation Network Contribution

0.0510

From 5 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 11 citers.

Improved ESI-MS Sensitivity via an Imidazolium Tag (DAPMI-ITag) for Precise Sialic Acid Detection in Human Serum and CMAH-Null Mouse Tissues
Analytical Chemistry20252 citations47 referencesContributes 0.023
Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies
Frontiers in Immunology20257 citations163 referencesContributes 0.013
Genetic and epigenetic determinants of fetal alcohol spectrum disorders: Toward a precision medicine approach
Experimental and Molecular Pathology20255 citations146 referencesContributes 0.012
Mechanisms of Acetaldehyde-Induced Organ Injury via Impairment of Vascular Endothelial Cells
Vascular Health and Risk Management20251 citations91 referencesContributes 0.008
A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies
Addiction20261 citations175 referencesContributes 0.004

Authors (71)

José Jaime Martínez‐Magaña ORCID,Natasia S. Courchesne‐Krak ORCID,Renata B. Cupertino ORCID,Laura Vilar‐Ribó ORCID,Sevim B. Bianchi ORCID

Live enrichment

PubMed:38580523 PMC:PMC11121167 OpenAlex:https://openalex.org/W4393924815

NCATS NIH HHS

Grant: UL1 TR001863

NIDA NIH HHS

Grant: R21 DA050160

NIAAA NIH HHS

Grant: K01 AA030083

NIMH NIH HHS

Grant: R25 MH081482

CSRD VA

Grant: IK2 CX002095

NIAAA NIH HHS

Grant: L40 AA031140

NHGRI NIH HHS

Grant: R01 HG012869

CSRD VA

Grant: I01 CX001849

NIMH NIH HHS

Grant: K01 MH121659

NIDA NIH HHS

Grant: DP1 DA054394

NIAAA NIH HHS

Grant: P50 AA012870

National Institutes of Health

Grant: 5R21DA050160-02

Integrative Epigenomic Mapping of Co-Morbid OUD and PTSD

National Institutes of Health

Grant: 5K01MH121659-04

A framework enabling the genomic analysis of psychiatric traits across admixed populations.

National Institutes of Health

Grant: 5IK2CX002095-03

Identifying Biomarkers of Post-traumatic Stress Disorder in U.S. Veterans using an Integrative Multi-Omics Approach

National Institutes of Health

Grant: 2R25MH081482-16

Interdisciplinary Research Fellowship in NeuroAIDS

National Institutes of Health

Grant: 5DP1DA054394-03

Building Bridges to Allow Cross-species Translational genetics for the Study of Addiction

National Institutes of Health

Grant: 1K01AA030083-01

Mass Multivariate Derivation and Validation of AUD Biotypes using Developmental Imaging and Genomic Approaches

National Institutes of Health

Grant: 2P50AA012870-06

Administrative Core

FWCI

4.11

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttp://www.thelancet.com/article/S235239642400121X/pdf

publisherhttp://www.thelancet.com/article/S235239642400121X/pdf

publisherhttps://api.elsevier.com/content/article/PII:S235239642400121X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S235239642400121X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ebiom.2024.105086

Fields of Study

Alcohol Consumption and Health EffectsSubstance Abuse Treatment and OutcomesGenetic Associations and Epidemiology03 medical and health sciences0305 other medical scienceHumansMendelian Randomization AnalysisPolymorphism, Single NucleotideAlcohol DrinkingGenome-Wide Association StudyPhenotypeFemaleCohort StudiesMalePhenomicsGenetic Predisposition to DiseaseAlcohol DehydrogenaseGenotypeAlleles

MeSH Terms

PhenomicsAlcohol DehydrogenaseAlcohol DrinkingAllelesFemaleGenotypeHumansMalePhenotypeCohort StudiesGenetic Predisposition to DiseasePolymorphism, Single NucleotideGenome-Wide Association StudyMendelian Randomization Analysis

Keywords

PhenomeADH1BSingle-nucleotide polymorphismGenome-wide association studyMedicineCohortMinor allele frequencyGeneticsBiologyPhenotypeInternal medicineGeneGenotypeAlcoholPhewasAdh1cRs1229984Metabolising Enzyme GenesMaleMedical SciencesAlcohol Drinking610Polymorphism, Single NucleotideBiomedical InformaticsCohort StudiesMedical SpecialtiesMedicine and Health Sciencesand ImmunityHumansGenetic Predisposition to DiseasePolymorphismPhenomicsAllelesBiological PhenomenaCell PhenomenaAlcohol DehydrogenaseLife SciencesGenetics and GenomicsSingle NucleotideArticlesMendelian Randomization AnalysisMedical Molecular BiologyFemaleMedical Genetics

Sustainable Development Goals

SDG 0: Good health and well-being

Characterizing genetic pathways for tobacco use by sex and across the lifespan

10.17920/g95875University of California Office of the President