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Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease

EBioMedicine(2024)10.1016/j.ebiom.2024.105232Source: DataRank Database

Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease is a research paper published in EBioMedicine (2024). On theSindex it has a DataRank of 0.470. It has been cited 22 times.

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0.470DataRank · unranked

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Open Access22 citations

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Enrichment:Funding (7 grants)OA: goldTopics (20)IDs (PubMed, PMC)Annotations (3)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Base Score 100%Citation Network 0%

Base Score Contribution

0.470

From this paper's citation signal

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Authors (22)

Kristina M. Garske ORCID,Uma Thanigai Arasu,Asha Kar ORCID,Zong Miao ORCID,Marcus Alvarez ORCID

Live enrichment

PubMed:38991381 PMC:PMC11663762

NIDDK NIH HHS

Grant: R01 DK132775

NHLBI NIH HHS

Grant: R01 HL170604

NIDDK NIH HHS

Grant: P30 DK041301

NHGRI NIH HHS

Grant: R01 HG010505

Novo Nordisk Fonden

Grant: NNF23SA0083953

NIEHS NIH HHS

Grant: F32 ES034668

NIH

goldLicense: cc-by

publisherhttps://doi.org/10.1016/j.ebiom.2024.105232

publisherhttps://api.elsevier.com/content/article/PII:S2352396424002676?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2352396424002676?httpAccept=text/plain

repositoryhttps://escholarship.org/content/qt2fk3w0xb/qt2fk3w0xb.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11663762/pdf/main.pdf

MeSH Terms

Cell NucleusHumansGenetic Predisposition to DiseaseSequence Analysis, RNAGene Expression RegulationPolymorphism, Single NucleotideQuantitative Trait LociAdipogenesisProtein Phosphatase 2Genome-Wide Association StudyObesity, AbdominalSingle-Cell AnalysisNon-alcoholic Fatty Liver Disease

Keywords

colocalizationabdominal obesityGenome-wide Association Study (Gwas)Expression Quantitative Trait Loci (Eqtl)Waist-Hip Ratio Adjusted For Body Mass Index (Whradjbmi)Metabolic Dysfunction-associated Steatotic Liver Disease (Masld)Single-nucleus Rna-sequencing (Snrna-seq)

Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease

FAIR Checklist

DataRank Breakdown

Authors (22)

Funding (7 grants)

Open Access

Topics

Annotations (Europe PMC)