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Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice

EBioMedicine(2024)10.1016/j.ebiom.2024.105361Source: DataRank Database

Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice is a research paper published in EBioMedicine (2024). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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Enrichment:Funding (5 grants)Impact (FWCI 2.89)OA: goldTopics (74)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (20)

Fernanda Ana‐Sosa‐Batiz,Julia Timis,Norazizah Shafee ORCID,Erin Maule,Paolla Beatriz Almeida Pinto

Live enrichment

PubMed:39353281 PMC:PMC11472634 OpenAlex:https://openalex.org/W4402975482

NIAID NIH HHS

Grant: U19 AI142790

National Institutes of Health

Grant: 5R44AI157900-03

Triple humanized ACE2-TMPRSS-FcGRT mouse models for COVID research in the C57BU6 and BALBIc backgrounds.

National Institutes of Health

Grant: 5U19AI142790-04

Consortium for Immunotherapeutics against Emerging Viral Threats

National Institutes of Health

GHR Foundation

FWCI

2.89

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.ebiom.2024.105361

publisherhttps://doi.org/10.1016/j.ebiom.2024.105361

publisherhttps://api.elsevier.com/content/article/PII:S2352396424003979?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2352396424003979?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39353281

Fields of Study

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studiesvaccines and immunoinformatics approaches0301 basic medicine03 medical and health sciencesAnimalsSARS-CoV-2Angiotensin-Converting Enzyme 2COVID-19MiceHumansTh2 CellsTh1 CellsDisease Models, AnimalGene Knock-In TechniquesMice, TransgenicSerine EndopeptidasesLungAntibodies, ViralMice, Inbred C57BLMice, Inbred BALB CSARS-CoV-2 variants

MeSH Terms

Angiotensin-Converting Enzyme 2COVID-19SARS-CoV-2AnimalsAntibodies, ViralDisease Models, AnimalHumansLungMice, Inbred BALB CMice, Inbred C57BLMice, TransgenicSerine EndopeptidasesTh1 CellsTh2 CellsMiceGene Knock-In Techniques

Keywords

VirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Immune systemCoronavirus disease 2019 (COVID-19)BiologyImmunology2019-20 coronavirus outbreakMedicinePathologyBalb/CDELTAB cellsMouse ModelC57bl/6Cd8 T CellsCd4 T CellsHace2Omicron Ba.1Htmprss2Mice, Inbred BALB CSARS-CoV-2Serine EndopeptidasesCOVID-19Mice, TransgenicArticlesTh1 CellsAntibodies, ViralMice, Inbred C57BLMiceDisease Models, AnimalTh2 CellsAnimalsHumansAngiotensin-Converting Enzyme 2Gene Knock-In TechniquesLung

Sustainable Development Goals

SDG 0: Good health and well-being

Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice

FAIR Checklist

Authors (20)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)