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Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort

EBioMedicine(2025)10.1016/j.ebiom.2025.105866Source: DataRank Database

Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort is a research paper published in EBioMedicine (2025). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 5.59)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Xinyuan Zhang ORCID,Eric A. Macklin ORCID,Jian Wang ORCID,Armin Bayati ORCID,Johannes M. Dijkstra ORCID

Live enrichment

PubMed:40773926 PMC:PMC12354789 OpenAlex:https://openalex.org/W4413009061

Aligning Science Across Parkinson's

Grant: ASAP-237603

National Institutes of Health

Grant: 5R01NS102735-02

MC1R basis of melanoma-Parkinson's link and neuroprotective potential of MC1R

National Institutes of Health

Grant: 5R01NS126260-02

Biomarkers and risk factors for prodromal Parkinson's disease and its progression

National Institute of Neurological Disorders and Stroke

Michael J. Fox Foundation for Parkinson's Research

FWCI

5.59

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://www.thelancet.com/pdfs/journals/ebiom/PIIS2352-3964(25)00310-X.pdf

publisherhttps://www.thelancet.com/pdfs/journals/ebiom/PIIS2352-3964(25)00310-X.pdf

publisherhttps://api.elsevier.com/content/article/PII:S235239642500310X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S235239642500310X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ebiom.2025.105866

Fields of Study

Parkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsVoice and Speech Disorders03 medical and health sciences0302 clinical medicineHumansParkinson Diseasealpha-SynucleinDisease ProgressionMaleFemaleAgedMiddle AgedLeucine-Rich Repeat Serine-Threonine Protein Kinase-2BiomarkersCohort StudiesGlucosylceramidase

MeSH Terms

Leucine-Rich Repeat Serine-Threonine Protein Kinase-2AgedFemaleGlucosylceramidaseHumansMaleMiddle AgedParkinson DiseaseCohort StudiesBiomarkersDisease Progressionalpha-Synuclein

Keywords

Parkinson's diseaseDiseaseCohortMedicineSeedingBiologyPathologyProgressionLrrk2GbaΑ-synuclein Seed Amplification AssayMaleParkinson DiseaseArticlesMiddle AgedLeucine-Rich Repeat Serine-Threonine Protein Kinase-2ArticleCohort Studiesalpha-SynucleinDisease ProgressionHumansGlucosylceramidaseFemaleBiomarkersAged

Sustainable Development Goals

SDG 0: Zero hunger