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Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112265Source: DataRank Database

Design, synthesis and biological evaluation of novel O-carbamoyl ferulamide derivatives as multi-target-directed ligands for the treatment of Alzheimer’s disease is a research paper published in European Journal of Medicinal Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 51 times.

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0DataRank · unranked

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Open Access51 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)OA: greenTopics (49)IDs (PubMed)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Keren Wang ORCID,Ping Bai ORCID,Anguo Wu ORCID,Jian Shi ORCID,Wenmin Liu

Live enrichment

PubMed:32240904

Key Scientific Research Project of Colleges and Universities in Henan Province

Grant: 20A350006

China Scholarship Council

Grant: 201808410456

NIH HHS

Grant: S10 OD023517

greenLicense: https://www.elsevier.com/legal/tdmrep-license

repositoryhttps://doi.org/10.7270/q2w099j0

publisherhttps://api.elsevier.com/content/article/PII:S0223523420302324?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0223523420302324?httpAccept=text/plain

Fields of Study

Alzheimer DiseaseAmidesAmyloid beta-PeptidesAnimalsCell LineCell SurvivalDisease Models, AnimalDose-Response Relationship, DrugDrug DesignHumansLigandsMiceMice, Inbred StrainsMicrosomes, LiverMolecular StructurePeptide FragmentsPositron Emission Tomography Computed TomographyProtein AggregatesRatsStructure-Activity RelationshipZebrafish

MeSH Terms

Keywords

Alzheimer’s diseaseMetabolism in vitroMulti-function agentsO-carbamoyl ferulamide derivativesPET-CT imagingScopolamine-induced cognitive impairmentZebrafish AD