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Synthesis and biological evaluation of novel FiVe1 derivatives as potent and selective agents for the treatment of mesenchymal cancers

European Journal of Medicinal Chemistry(2022)10.1016/j.ejmech.2022.114638Source: DataRank Database

Synthesis and biological evaluation of novel FiVe1 derivatives as potent and selective agents for the treatment of mesenchymal cancers is a research paper published in European Journal of Medicinal Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 9 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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Cite:

Linked data & code

CCDC 2070504: Experimental Crystal Structure Determination · Cambridge Crystallographic Data Centre

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.87)OA: greenTopics (56)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (8)

Aaron D. Pearson ORCID,Eileen L. Tang,Nick A. Kuburich ORCID,Sendurai A. Mani ORCID,Peter G. Schultz ORCID

Live enrichment

PubMed:36001933 PMC:PMC10377566 OpenAlex:https://openalex.org/W4293105409

National Cancer Institute

Grant: 1R01CA200970-01A1

Preclinical characterization of EMT/CSC-specific small molecule inhibitors for TNBCs

NCI NIH HHS

Grant: R01 CA200970

National Institutes of Health

FWCI

0.87

Citation Percentile

0.7%

Citation Trend

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10377566/pdf/nihms-1916857.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0223523422005402?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0223523422005402?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10377566

Fields of Study

Skin and Cellular Biology ResearchCellular Mechanics and InteractionsMicrotubule and mitosis dynamics0301 basic medicine03 medical and health sciences0302 clinical medicineAnimalsCell Line, TumorEpithelial-Mesenchymal TransitionMiceMitosisPhosphorylationSarcomaVimentin

MeSH Terms

AnimalsMitosisPhosphorylationSarcomaVimentinCell Line, TumorMiceEpithelial-Mesenchymal Transition

Keywords

Mesenchymal stem cellChemistryIn vivoPotencyCancer researchPharmacologyCell growthBioavailabilityCancerCancer cellFibrosarcomaEpithelial–mesenchymal transitionCellCell cultureBiochemistryIn vitroCell biologyDownregulation and upregulationBiologyInternal medicineMedicinePathologyBiotechnologyVimentinStructure-activity relationshipMedicinal chemistryMesenchymal CancerMiceEpithelial-Mesenchymal TransitionCell Line, TumorAnimalsMitosisSarcomaPhosphorylation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

CCDC 2070504: Experimental Crystal Structure Determination

10.5517/ccdc.csd.cc27hjgrCambridge Crystallographic Data Centre