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Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115123Source: DataRank Database

Design, synthesis, and evaluation of substituted alkylindoles that activate G protein-coupled receptors distinct from the cannabinoid CB1 and CB2 receptors is a research paper published in European Journal of Medicinal Chemistry (2023). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 0.00)OA: greenTopics (29)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (13)

Cong Xu ORCID,Faith R. Kreitzer,Dow P. Hurst ORCID,Khalil Eldeeb ORCID,Jim Wager‐Miller ORCID

Live enrichment

PubMed:36708677 PMC:PMC10917149 OpenAlex:https://openalex.org/W4318450038

National Institutes of Health

Grant: DA03590

NIDA CTN

Grant: DA011322

NIDA CTN

Grant: DA0144861

NIDA CTN

Grant: DA021358

NIDA CTN

Grant: DA021696

NIDA CTN

Grant: DA042157

NCI NIH HHS

Grant: R01 CA244213

NIDA NIH HHS

Grant: K05 DA021358

NIDA NIH HHS

Grant: R01 DA021285

NINDS NIH HHS

Grant: R21 NS106924

NIDA NIH HHS

Grant: R01 DA011322

NIDA NIH HHS

Grant: K05 DA021696

NIDA NIH HHS

Grant: R01 DA003590

NIDA NIH HHS

Grant: R01 DA042157

FWCI

0.00

Citation Percentile

0.0%

greenLicense: https://doi.org/10.15223/policy-004

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10917149/pdf/nihms-1965279.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0223523423000387?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0223523423000387?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10917149

Fields of Study

Cannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on BehaviorPharmacological Receptor Mechanisms and Effects

MeSH Terms

CannabinoidsHumansMorpholinesNaphthalenesGuanosine 5'-O-(3-Thiotriphosphate)Receptors, G-Protein-CoupledReceptors, CannabinoidReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2BenzoxazinesHEK293 Cells

Keywords

G protein-coupled receptorPharmacophoreChemistryCannabinoid receptorCannabinoidG proteinIn silicoReceptorStereochemistryBiochemistryAgonistGeneG protein-coupled receptorsCannabinoidsAlkylindoles