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SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115125Source: DataRank Database

SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis is a research paper published in European Journal of Medicinal Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Linked data & code

BindingDB Entry 50019817: SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis. · BindingDB

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 1.16)OA: greenTopics (34)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (8)

Pooja Hegde,Venugopal Pujari,Marzena Brinkmann,David Z. Wilkins,Tanya Parish ORCID

Live enrichment

PubMed:36682292 PMC:PMC9975056 OpenAlex:https://openalex.org/W4317781168

NIAID NIH HHS

Grant: R01 AI049151

NIAID NIH HHS

Grant: R56 AI049151

FWCI

1.16

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9975056/pdf/nihms-1867188.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0223523423000405?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0223523423000405?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9975056

Fields of Study

Tuberculosis Research and EpidemiologyBiochemical and Molecular ResearchATP Synthase and ATPases ResearchHumansMycobacterium tuberculosisNaphtholsTuberculosisElectron TransportAntitubercular Agents

MeSH Terms

Antitubercular AgentsElectron TransportHumansMycobacterium tuberculosisNaphtholsTuberculosis

Keywords

ChemistryMycobacterium tuberculosisEnzymeIn vivoStereochemistryBedaquilineSmall moleculeTuberculosisStructure–activity relationshipBiochemistryIn vitroBiologySARMTBMenaquinoneMenaPiperidine Derivatives1,4-Dihydroxy-2-naphthoate PrenyltransferaseMena Inhibitors

Sustainable Development Goals

SDG 0: Good health and well-being

BindingDB Entry 50019817: SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis.

10.7270/q2dn49fzBindingDB

SAR study of piperidine derivatives as inhibitors of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis

FAIR Checklist

Authors (8)

Funding (2 grants)

Impact

Open Access

Topics

Linked Datasets (1)

Annotations (Europe PMC)